Continuous manufacturing–the Green Chemistry promise?

L Rogers, KF Jensen - Green chemistry, 2019 - pubs.rsc.org
Continuous manufacturing and Green Chemistry, are two promising approaches to
synthesis with underutilized potential that are gaining traction by the wider pharmaceutical …

Why flow means green–Evaluating the merits of continuous processing in the context of sustainability

D Dallinger, CO Kappe - Current Opinion in Green and Sustainable …, 2017 - Elsevier
Highlights•Green processes need to be scalable to have the greatest environmental
impact.•Focus on continuous API synthesis on larger (industrial) scale.•Main drivers for …

Pharmaceutical roundtable study demonstrates the value of continuous manufacturing in the design of greener processes

P Poechlauer, J Colberg, E Fisher… - … Process Research & …, 2013 - ACS Publications
The American Chemical Society (ACS) Green Chemistry Institute (GCI) Pharmaceutical
Roundtable conducted a study to elucidate the value of continuous processing, which had …

Continuous flow reactors: a perspective

C Wiles, P Watts - Green Chemistry, 2012 - pubs.rsc.org
With aspects of continuous processing featuring heavily in efforts towards increasing the
'green'prospects of pharmaceutical and fine chemical manufacturing, this article focuses on …

Role of continuous flow processes in green manufacturing of pharmaceuticals and specialty chemicals

JA Bennett, ZS Campbell, M Abolhasani - Current Opinion in Chemical …, 2019 - Elsevier
Highlights•An overview of the elements of continuous flow processes.•Synopsis of recent
advancements in green continuous manufacturing strategies.•Synopsis of recent …

Continuous processing in the manufacture of active pharmaceutical ingredients and finished dosage forms: an industry perspective

P Poechlauer, J Manley, R Broxterman… - … Process Research & …, 2012 - ACS Publications
Continuous manufacturing as a way of producing fine chemicals, active pharmaceutical
ingredients, and finished dosage forms is gaining widespread attention. Although potential …

A perspective on continuous flow chemistry in the pharmaceutical industry

M Baumann, TS Moody, M Smyth… - … Process Research & …, 2020 - ACS Publications
Continuous flow manufacture is an innovative technology platform, which is gaining
momentum within the pharmaceutical industry. The key advantages of continuous flow …

The role of flow in green chemistry and engineering

SG Newman, KF Jensen - Green chemistry, 2013 - pubs.rsc.org
Flow chemistry and continuous processing can offer many ways to make synthesis a more
sustainable practice. These technologies help bridge the large gap between academic and …

[图书][B] Continuous manufacturing of pharmaceuticals

P Kleinebudde, J Khinast, J Rantanen - 2017 - books.google.com
A comprehensive look at existing technologies and processes for continuous manufacturing
of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical …

Forbidden chemistries—paths to a sustainable future engaging continuous processing

B Gutmann, CO Kappe - Journal of Flow Chemistry, 2017 - akjournals.com
Optimizing current chemical processes alone does not yield the improvements required in
the fine chemical and pharmaceutical industries. At least partially, a switch from batch to …