Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials

G Grosso, A Pajak, S Marventano, S Castellano… - PloS one, 2014 - journals.plos.org
Background Despite omega-3 polyunsaturated fatty acids (PUFA) supplementation in
depressed patients have been suggested to improve depressive symptomatology, previous …

Efficacy of omega-3 PUFAs in depression: a meta-analysis

Y Liao, B Xie, H Zhang, Q He, L Guo… - Translational …, 2019 - nature.com
We conducted this meta-analysis of double-blind randomized placebo-controlled trials to
estimate the efficacy of omega-3 polyunsaturated fatty acids (PUFAs), especially …

Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder

RJT Mocking, I Harmsen, J Assies, MWJ Koeter… - Translational …, 2016 - nature.com
Omega-3 polyunsaturated fatty acid (PUFA) supplementation has been proposed as
(adjuvant) treatment for major depressive disorder (MDD). In the present meta-analysis, we …

Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis

MH Bloch, J Hannestad - Molecular psychiatry, 2012 - nature.com
We conducted a meta-analysis of randomized, placebo-controlled trials of omega-3 fatty
acid (FA) treatment of major depressive disorder (MDD) in order to determine efficacy and to …

Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression

B Hallahan, T Ryan, JR Hibbeln, IT Murray… - The British Journal of …, 2016 - cambridge.org
BackgroundTrials evaluating efficacy of omega-3 highly unsaturated fatty acids (HUFAs) in
major depressive disorder report discrepant findings. AimsTo establish the reasons …

A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids.

PY Lin, KP Su - Journal of Clinical Psychiatry, 2007 - psychiatrist.com
Objective: Evidence has indicated an association between depression and low dietary
intake of omega-3 polyunsaturated fatty acids (PUFAs). However, clinical trials examining …

Omega‐3 fatty acids for depression in adults

KM Appleton, PD Voyias, HM Sallis… - Cochrane Database …, 2021 - cochranelibrary.com
Background Major depressive disorder (MDD) is highly debilitating, difficult to treat, has a
high rate of recurrence, and negatively impacts the individual and society as a whole. One …

Meta-analysis of the effects of eicosapentaenoic acid (EPA) in clinical trials in depression

ME Sublette, SP Ellis, AL Geant… - The Journal of clinical …, 2011 - psychiatrist.com
Objective: Randomized trials of omega-3 polyunsaturated fatty acid (PUFA) treatment for
depression have differed in outcome. Recent meta-analyses ascribe discrepancies to …

EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta …

JG Martins - Journal of the American College of Nutrition, 2009 - Taylor & Francis
Background: Epidemiologic and case-control data suggest that increased dietary intake of
omega-3 long-chain polyunsaturated fatty acids (ω3 LC-PUFAs) may be of benefit in …

Systematic review and meta-analysis of omega-3-fatty acids in elderly patients with depression

JH Bae, G Kim - Nutrition Research, 2018 - Elsevier
One of the typical symptoms of a psychological crisis is depression, an increasing concern in
the elderly population. Although omega-3-polyunsaturated fatty acids (PUFAs) are reported …