Cerebrospinal fluid flow

DH Kelley, JH Thomas - Annual Review of Fluid Mechanics, 2023 - annualreviews.org
Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and
through the brain transports not only those water-like fluids but also any solutes they carry …

Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases

PK Eide, LM Valnes, EK Lindstrøm, KA Mardal… - Fluids and Barriers of …, 2021 - Springer
Background Several central nervous system diseases are associated with disturbed
cerebrospinal fluid (CSF) flow patterns and have typically been characterized in vivo by …

Fluid dynamics of cerebrospinal fluid flow in perivascular spaces

JH Thomas - Journal of the Royal Society Interface, 2019 - royalsocietypublishing.org
The flow of cerebrospinal fluid along perivascular spaces (PVSs) is an important part of the
brain's system for delivering nutrients and eliminating metabolic waste products (such as …

Fluid transport in the brain

MK Rasmussen, H Mestre… - Physiological …, 2022 - journals.physiology.org
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

Fluid flow and mass transport in brain tissue

LA Ray, JJ Heys - Fluids, 2019 - mdpi.com
Despite its small size, the brain consumes 25% of the body's energy, generating its own
weight in potentially toxic proteins and biological debris each year. The brain is also the only …

Cerebrospinal fluid dynamics in the human cranial subarachnoid space: an overlooked mediator of cerebral disease. I. Computational model

S Gupta, M Soellinger… - Journal of the …, 2010 - royalsocietypublishing.org
Abnormal cerebrospinal fluid (CSF) flow is suspected to be a contributor to the pathogenesis
of neurodegenerative diseases such as Alzheimer's through the accumulation of toxic …

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

SW Bothwell, D Janigro, A Patabendige - Fluids and Barriers of the CNS, 2019 - Springer
The fine balance between the secretion, composition, volume and turnover of cerebrospinal
fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance …

The glymphatic system: Current understanding and modeling

T Bohr, PG Hjorth, SC Holst, S Hrabětová, V Kiviniemi… - IScience, 2022 - cell.com
We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …

Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism

BJ Jin, AJ Smith, AS Verkman - Journal of General Physiology, 2016 - rupress.org
A “glymphatic system,” which involves convective fluid transport from para-arterial to
paravenous cerebrospinal fluid through brain extracellular space (ECS), has been proposed …

Cerebrospinal fluid mechanics and its coupling to cerebrovascular dynamics

AA Linninger, K Tangen, CY Hsu… - Annual Review of Fluid …, 2016 - annualreviews.org
Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …