[HTML][HTML] Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages

D Chen, X Zhang, Z Li, B Zhu - Theranostics, 2021 - ncbi.nlm.nih.gov
Macrophages phagocytize pathogens to initiate innate immunity and products from the
tumor microenvironment (TME) to mediate tumor immunity. The loss of tumor-associated …

[HTML][HTML] The role of metabolic plasticity of tumor-associated macrophages in shaping the tumor microenvironment immunity

MN Hasan, O Capuk, SM Patel, D Sun - Cancers, 2022 - mdpi.com
Simple Summary Tumor associated macrophages (TAMs) support disease progression by
providing tumor cells cytokines and chemokines necessary for malignant growth and …

[HTML][HTML] Metabolic reprograming of tumor-associated macrophages

A Puthenveetil, S Dubey - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
A large body of scientific evidence corroborated by clinical and animal model experiments
indicates that tumor-associated macrophages (TAMs) play a crucial role in tumor …

The role of macrophages in the tumor microenvironment and tumor metabolism

P Sadhukhan, TY Seiwert - Seminars in Immunopathology, 2023 - Springer
The complexity and plasticity of the tumor microenvironment (TME) make it difficult to fully
understand the intratumoral regulation of different cell types and their activities …

[HTML][HTML] Macrophages and metabolism in the tumor microenvironment

I Vitale, G Manic, LM Coussens, G Kroemer, L Galluzzi - Cell metabolism, 2019 - cell.com
Tumor-associated macrophages (TAMs) constitute a plastic and heterogeneous cell
population of the tumor microenvironment (TME) that can account for up to 50% of some …

[HTML][HTML] Reprogramming tumor-associated macrophages as a unique approach to target tumor immunotherapy

SU Khan, MU Khan, M Azhar Ud Din, IM Khan… - Frontiers in …, 2023 - frontiersin.org
In the last ten years, it has become increasingly clear that tumor-infiltrating myeloid cells
drive not just carcinogenesis via cancer-related inflammatory processes, but also tumor …

Comprehensive proteomics analysis reveals metabolic reprogramming of tumor-associated macrophages stimulated by the tumor microenvironment

D Liu, C Chang, N Lu, X Wang, Q Lu… - Journal of Proteome …, 2017 - ACS Publications
Tumor-associated macrophages (TAMs) are major components of the tumor
microenvironment. Although a role for TAMs in promoting tumor progression has been …

Cellular metabolism of tumor‐associated macrophages–functional impact and consequences

K Rabold, MG Netea, GJ Adema… - FEBS letters, 2017 - Wiley Online Library
Macrophages are innate immune cells that play a role not only in host defense against
infections, but also in the pathophysiology of autoimmune and autoinflammatory disorders …

[HTML][HTML] Macrophages are metabolically heterogeneous within the tumor microenvironment

X Geeraerts, J Fernandez-Garcia, FJ Hartmann… - Cell reports, 2021 - cell.com
Macrophages are often prominently present in the tumor microenvironment, where distinct
macrophage populations can differentially affect tumor progression. Although metabolism …

[HTML][HTML] Metabolism, metabolites, and macrophages in cancer

M Li, Y Yang, L Xiong, P Jiang, J Wang, C Li - Journal of hematology & …, 2023 - Springer
Tumour-associated macrophages (TAMs) are crucial components of the tumour
microenvironment and play a significant role in tumour development and drug resistance by …