Attention-deficit/hyperactivity disorder (ADHD) is a severely impairing neurodevelopmental
disorder with a prevalence of 5% in children and adolescents and of 2.5% in adults …

Cannabis use is a heritable trait that has been associated with adverse mental health
outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to …

Substance use disorder (SUD) often co‐occur at high prevalence with other psychiatric
conditions. Among them, attention‐deficit and hyperactivity disorder (ADHD) is present in …

A genome-wide association (GWA) study with pooled DNA in adult attention-
deficit/hyperactivity disorder (ADHD) employing~ 500K SNP markers identifies novel risk …

Background Variation in liability to cannabis use disorder has a strong genetic component
(estimated twin and family heritability about 50–70%) and is associated with negative …

Despite moderate heritability, only one study has identified genome-wide significant loci for
cannabis-related phenotypes. We conducted meta-analyses of genome-wide association …

Importance Cannabis dependence (CAD) is a serious problem worldwide and is of growing
importance in the United States because cannabis is increasingly available legally …

Liability to alcohol dependence (AD) is heritable, but little is known about its complex
polygenic architecture or its genetic relationship with other disorders. To discover loci …

Aims To review three key and controversial comorbidities of cannabis use—other illicit drug
use, psychosis and depression, as well as suicide, from a genetically informed perspective …

Cannabis is the most widely produced and consumed illicit psychoactive substance
worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence …