Synopsis The DNA polymerase of human herpes viruses, including cytomegalovirus (CMV),
and the reverse transcriptase of human immunodeficiency virus (HIV) are selectively …

Synopsis The pyrophosphate analogue, foscarnet, selectively inhibits the DNA polymerase
of human herpes viruses, including cytomegalovirus, and the reverse transcriptase of HIV …

Ten patients with acquired immunodeficiency syndrome with newly diagnosed
cytomegalovirus (CMV) retinitis were treated with an induction regimen of intravenous …

Six patients with human immunodeficiency virus were given foscarnet in oral solution, 4000
mg every 6 hours for 3 days, followed by a washout period for 2 days and continuous …

Materials and Methods Foscarnet therapy. We treated 11 patients with AIDS and
cytomegalovirus retinitis (diagnosed by typical funduscopic appearance) with an induction …

Herpes simplex virus (HSV) resistant to acyclovir can produce persistent mucocutaneous
ulcerative disease in patients with the acquired immunodeficiency syndrome (AIDS). The …

Foscarnet (phosphonoformic acid) is a pyrophosphate analog that inhibits the replication of
human immunodeficiency virus type 1 (HIV-1) in vitro and in patients with AIDS. HIV-1 …

Fifty seven episodes of severe cytomegalovirus (CMV) infection were treated with iv
foscarnet in 13 bone marrow and 33 renal graft recipients. The ranges of the daily dose …

This short letter describes the unfortunate sequence of events in a young woman initially
treated successfully for primary herpes simplex virus (HSV) with iv acyclovir (5 mg/kg 3 times …

▪ Objective: To evaluate foscarnet sodium in treating cytomegalovirus retinitis in patients with
AIDS.▪ Patients: Twenty-four previously untreated persons with AIDS and cytomegalovirus …