[HTML][HTML] Expression of epigenetic machinery genes is sensitive to maternal obesity and weight loss in relation to fetal growth in mice

PE Panchenko, S Voisin, M Jouin, L Jouneau… - Clinical …, 2016 - Springer
Background Maternal obesity impacts fetal growth and pregnancy outcomes. To counteract
the deleterious effects of obesity on fertility and pregnancy issue, preconceptional weight …

[HTML][HTML] Overweight and obesity in pregnancy: their impact on epigenetics

C Reichetzeder - European journal of clinical nutrition, 2021 - nature.com
Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

[HTML][HTML] Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice

IE Sasson, AP Vitins, MA Mainigi, KH Moley… - Diabetologia, 2015 - Springer
Aims/hypothesis Maternal obesity is associated with an increased risk of obesity and
impaired glucose homeostasis in offspring. However, it is not known whether a gestational …

Maternal obesity, maternal overnutrition and fetal programming: effects of epigenetic mechanisms on the development of metabolic disorders

E Şanlı, S Kabaran - Current genomics, 2019 - ingentaconnect.com
Background: Maternal obesity and maternal overnutrition, can lead to epigenetic alterations
during pregnancy and these alterations can influence fetal and neonatal phenotype which …

[HTML][HTML] Maternal obesity during pregnancy and lactation influences offspring obesogenic adipogenesis but not developmental adipogenesis in mice

D Sellayah, H Thomas, SA Lanham, FR Cagampang - Nutrients, 2019 - mdpi.com
Obesity is an escalating health crisis of pandemic proportions and by all accounts it has yet
to reach its peak. Growing evidence suggests that obesity may have its origins in utero …

Effects of maternal obesity on fetal programming: molecular approaches

C Neri, AG Edlow - Cold Spring Harbor …, 2016 - perspectivesinmedicine.cshlp.org
Maternal obesity has become a worldwide epidemic. Obesity and a high-fat diet have been
shown to have deleterious effects on fetal programming, predisposing offspring to adverse …

[PDF][PDF] Paternal obesity in a rodent model affects placental gene expression in a sex-specific manner

NK Binder, SA Beard, TJ Kaitu'u-Lino, S Tong… - …, 2015 - researchgate.net
Fetal growth restriction (FGR) is a major obstetric complication stemming from poor placental
development. We have previously demonstrated that paternal obesity in mice is associated …

Maternal obesity and prenatal programming

S Elshenawy, R Simmons - Molecular and cellular endocrinology, 2016 - Elsevier
Obesity is a significant and increasing public health concern in the United States and
worldwide. Clinical and epidemiological evidence clearly shows that genetic and …

Obesity phenotype induced by high-fat diet leads to maternal-fetal constraint, placental inefficiency, and fetal growth restriction in mice

APV Sanches, JL de Oliveira, MS Ferreira… - The Journal of …, 2022 - Elsevier
The aim of this study was to investigate certain parameters regarding the maternal-fetal
outcomes in a diet-induced obesity model. Obese, glucose-intolerant females who were …

[HTML][HTML] High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects

KM Luzzo, Q Wang, SH Purcell, M Chi, PT Jimenez… - PloS one, 2012 - journals.plos.org
Background Maternal obesity is associated with poor outcomes across the reproductive
spectrum including infertility, increased time to pregnancy, early pregnancy loss, fetal loss …