Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

Many promising therapeutic agents are limited by their inability to reach the systemic
circulation, due to the excellent barrier properties of biological membranes, such as the …

Human skin is a multilayered physiochemical barrier protecting the human body. The
stratum corneum (SC) is the outermost keratinized layer of skin through which only …

Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

We describe, for the first time, the microbial characterisation of hydrogel-forming polymeric
microneedle arrays and the potential for passage of microorganisms into skin following …

Microneedles (MNs) have become versatile platforms for minimally invasive transdermal
drug delivery devices. However, there are concerns about MN‐induced skin infections with …

Transdermal delivery systems have recently attracted a great interest due to its minimal
invasiveness and convenience. One latest technology in this field is the microneedle …

Microneedles are one of the most prominent approaches capable of physically disrupting
the stratum corneum without devastating the deeper tissues to deliver both small molecules …

There are increasing demands for long-term and controlled corneal drug delivery to treat
various ocular diseases. Although biodegradable ocular inserts or contact lenses have been …

Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …