Proteomic Profiling of Extracellular Vesicles Isolated from Plasma and Peritoneal Exudate in Mice Induced by Crotalus scutulatus scutulatus Crude Venom and Its …

A Reyes, JD Hatcher, E Salazar, J Galan, A Iliuk… - Toxins, 2023 - mdpi.com
Increased vascular permeability is a frequent outcome of viperid snakebite envenomation,
leading to local and systemic complications. We reported that snake venom cysteine-rich …

Crotalus scutulatus scutulatus Crude Venom and Its Purified Cysteine-Rich Secretory Protein (Css-CRiSP)

A Reyes, JD Hatcher, E Salazar, J Galan, A Iliuk… - …, 2023 - scholarworks.utrgv.edu
Increased vascular permeability is a frequent outcome of viperid snakebite envenomation,
leading to local and systemic complications. We reported that snake venom cysteine-rich …

Evaluation of signaling pathways profiling in human dermal endothelial cells treated by snake venom cysteine-rich secretory proteins (svCRiSPs) from north American …

M Suntravat, O Sanchez, A Reyes, A Cirilo… - Toxins, 2021 - mdpi.com
Cysteine-Rich Secretory Proteins (CRiSPs) are typically found in many snake venoms;
however, the role that these toxins play in the pathophysiology of snakebites is still unclear …

[HTML][HTML] Snake venom cysteine-rich secretory protein from Mojave rattlesnake venom (Css-CRiSP) induces acute inflammatory responses on different experimental …

E Salazar, A Cirilo, A Reyes, M Barrientos, J Galan… - Toxicon: X, 2024 - Elsevier
Snake venoms contain various molecules known for activating innate immunity and causing
local effects associated with increased vascular permeability, such as vascular leakage and …

Proteomic identification and quantification of snake venom biomarkers in venom and plasma extracellular vesicles

NK Willard, E Salazar, FA Oyervides, CS Wiebe… - Toxins, 2021 - mdpi.com
The global exploration of snakebites requires the use of quantitative omics approaches to
characterize snake venom as it enters into the systemic circulation. These omics approaches …

9A REVIEW ON SNAKE VENOM EXTRACELLULAR VESICLES: PAST TO PRESENT

K Nagendra, SM Bakkannavar, VR Bhat, FM Sirur - Toxicon, 2024 - Elsevier
Around 95% of snake venom is protein. Along with the soluble proteins, snake venom also
contains proteins encapsulated in vesicles known as Snake Venom Extracellular Vesicles …

Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

VC Carregari, L Rosa-Fernandes, P Baldasso… - Scientific reports, 2018 - nature.com
Proteins constitute almost 95% of snake venom's dry weight and are produced and released
by venom glands in a solubilized form during a snake bite. These proteins are responsible …

Extracellular Vesicles from Bothrops jararaca Venom Are Diverse in Structure and Protein Composition and Interact with Mammalian Cells

L Gonçalves-Machado, BRF Verçoza, FCS Nogueira… - Toxins, 2022 - mdpi.com
Snake venoms are complex cocktails of non-toxic and toxic molecules that work
synergistically for the envenoming outcome. Alongside the immediate consequences …

[HTML][HTML] Investigating possible biological targets of Bj-CRP, the first cysteine-rich secretory protein (CRISP) isolated from Bothrops jararaca snake venom

ME Lodovicho, TR Costa, CP Bernardes, DL Menaldo… - Toxicology letters, 2017 - Elsevier
Cysteine-rich secretory proteins (CRISPs) are commonly described as part of the protein
content of snake venoms, nevertheless, so far, little is known about their biological targets …

The isolation and characterization of a new snake venom cysteine-rich secretory protein (svCRiSP) from the venom of the Southern Pacific rattlesnake and its effect on …

M Suntravat, WE Cromer, J Marquez, JA Galan… - Toxicon, 2019 - Elsevier
A novel snake venom cysteine-rich secretory protein (svCRiSP), Hellerin, was purified from
C. o. helleri venom using sequential reverse phase and cation-exchange chromatography …