ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

A Dasari, VK Morris, CJ Allegra, C Atreya… - Nature reviews Clinical …, 2020 - nature.com
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …

The promise of circulating tumor DNA (ctDNA) in the management of early-stage colon cancer: a critical review

S Chakrabarti, H Xie, R Urrutia, A Mahipal - Cancers, 2020 - mdpi.com
Simple Summary Currently, the treatment for localized colon cancer consists of surgery and,
if the presence of residual cancer cells is suspected, chemotherapy following the surgery …

Circulating tumor DNA: an emerging tool in gastrointestinal cancers

OB Alese, N Cook, A Ortega-Franco… - American Society of …, 2022 - ascopubs.org
Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that
has come from primary or metastatic cancer sites. Neoplasm-specific genetic and epigenetic …

Circulating tumor DNA in precision oncology and its applications in colorectal cancer

MF Arisi, E Dotan, SV Fernandez - International Journal of Molecular …, 2022 - mdpi.com
Circulating tumor DNA (ctDNA) is a component of cell-free DNA (cfDNA) that is shed by
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …

The use of circulating tumor DNA to monitor and predict response to treatment in colorectal cancer

M Reece, H Saluja, P Hollington, CS Karapetis… - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer is one of the most common cancers worldwide and has a
high mortality rate following disease recurrence. Treatment efficacy is maximized by …

[HTML][HTML] Using circulating tumor DNA in colorectal cancer: current and evolving practices

M Malla, JM Loree, PM Kasi… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …

Circulating tumor DNA detection: A potential tool for colorectal cancer management

H Li, C Jing, J Wu, J Ni, H Sha, X Xu… - Oncology …, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …

ctDNA and adjuvant therapy for colorectal cancer: time to re-invent our treatment paradigm

M Naidoo, P Gibbs, J Tie - Cancers, 2021 - mdpi.com
Simple Summary There is currently a lack of useful tests to detect microscopic residual
disease in patients who have undergone surgery to remove their bowel cancer. This inability …

Early evaluation of circulating tumor DNA as marker of therapeutic efficacy in metastatic colorectal cancer patients (PLACOL study)

F Garlan, P Laurent-Puig, D Sefrioui, N Siauve… - Clinical Cancer …, 2017 - AACR
Purpose: Markers of chemotherapy efficacy in metastatic colorectal cancer (mCRC) are
essential for optimization of treatment strategies. We evaluated the applicability of early …

Clinical utility of circulating tumor DNA for colorectal cancer

H Osumi, E Shinozaki, K Yamaguchi… - Cancer …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is currently the most common type of cancer in Japan, and its
prognosis has improved because of development of diagnosis and advancement in …