miRNA studies in glaucoma: a comprehensive review of current knowledge and future perspectives
M Dobrzycka, A Sulewska, P Biecek… - International Journal of …, 2023 - mdpi.com
Glaucoma, a neurodegenerative disorder that leads to irreversible blindness, remains a
challenge because of its complex nature. MicroRNAs (miRNAs) are crucial regulators of …
challenge because of its complex nature. MicroRNAs (miRNAs) are crucial regulators of …
Identification of candidate miRNA biomarkers for glaucoma
AG Hindle, R Thoonen, JV Jasien… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: Glaucoma, a leading cause of blindness worldwide, often remains undetected until
irreversible vision loss has occurred. Treatments focus on lowering intraocular pressure …
irreversible vision loss has occurred. Treatments focus on lowering intraocular pressure …
MicroRNAs as biomarkers in glaucoma and potential therapeutic targets
B Martinez, PV Peplow - Neural regeneration research, 2022 - journals.lww.com
Glaucoma is a neurodegenerative disease in which optic nerve damage and visual field
defects occur. It is a leading cause of irreversible blindness. Its pathogenesis is largely …
defects occur. It is a leading cause of irreversible blindness. Its pathogenesis is largely …
miRNAs and genes involved in the interplay between ocular hypertension and primary open-angle glaucoma. Oxidative stress, inflammation, and apoptosis networks
J Raga-Cervera, JM Bolarin, JM Millan… - Journal of Clinical …, 2021 - mdpi.com
Glaucoma has no cure and is a sight-threatening neurodegenerative disease affecting more
than 100 million people worldwide, with primary open angle glaucoma (POAG) being the …
than 100 million people worldwide, with primary open angle glaucoma (POAG) being the …
[HTML][HTML] miRNA profile in three different normal human ocular tissues by miRNA-Seq
Purpose: Because microRNAs (miRNAs) have been associated with eye diseases, our study
aims to profile ocular miRNA expression in normal human ciliary body (CB), cornea, and …
aims to profile ocular miRNA expression in normal human ciliary body (CB), cornea, and …
Shared Molecular Pathways in Glaucoma and Other Neurodegenerative Diseases: Insights from RNA-Seq Analysis and miRNA Regulation for Promising Therapeutic …
CFM Vasconcelos, VT Ribas, H Petrs-Silva - Cells, 2023 - mdpi.com
Advances in RNA-sequencing technologies have led to the identification of molecular
biomarkers for several diseases, including neurodegenerative diseases, such as …
biomarkers for several diseases, including neurodegenerative diseases, such as …
microRNA profiling in glaucoma eyes with varying degrees of optic neuropathy by using next-generation sequencing
Purpose: To explore the microRNA (miRNA) profile and its putative role in glaucomatous
optic neuropathy by using next-generation sequencing. Methods: Aqueous humor (AH) …
optic neuropathy by using next-generation sequencing. Methods: Aqueous humor (AH) …
[HTML][HTML] Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: a pilot study
H Jayaram, JI Phillips, DC Lozano… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: MicroRNAs (miRNAs) are small, endogenous noncoding RNAs that have been
detected in human aqueous humor (AH). Prior studies have pooled samples to obtain …
detected in human aqueous humor (AH). Prior studies have pooled samples to obtain …
A common variant in MIR182 is associated with primary open-angle glaucoma in the NEIGHBORHOOD consortium
Purpose: Noncoding microRNAs (miRNAs) have been implicated in the pathogenesis of
glaucoma. We aimed to identify common variants in miRNA coding genes (MIR) associated …
glaucoma. We aimed to identify common variants in miRNA coding genes (MIR) associated …