The immunological basis of inflammatory bowel disease

FAR Silva, BL Rodrigues… - … research and practice, 2016 - Wiley Online Library
Inflammatory bowel diseases (IBDs) are chronic ailments, Crohn's disease and ulcerative
colitis being the most important. These diseases present an inflammatory profile and they …

Role of Th17 cells in the pathogenesis of human IBD

J Gálvez - International Scholarly Research Notices, 2014 - Wiley Online Library
The gastrointestinal tract plays a central role in immune system, being able to mount efficient
immune responses against pathogens, keeping the homeostasis of the human gut …

[HTML][HTML] Immunological pathogenesis of inflammatory bowel disease

SH Lee, J eun Kwon, ML Cho - Intestinal research, 2018 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic inflammatory state of the gastrointestinal tract
and can be classified into 2 main clinical phenomena: Crohn's disease (CD) and ulcerative …

Innate and adaptive immunity in inflammatory bowel disease

A Geremia, P Biancheri, P Allan, GR Corazza… - Autoimmunity …, 2014 - Elsevier
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
The exact cause of IBD remains unknown. Available evidence suggests that an abnormal …

[HTML][HTML] Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease

XR Xu, CQ Liu, BS Feng, ZJ Liu - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. The exact
etiology and pathology of IBD remain unknown. Available evidence suggests that an …

[HTML][HTML] Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease

ZJ Liu, PK Yadav, JL Su, JS Wang… - World journal of …, 2009 - ncbi.nlm.nih.gov
The etiopathology of inflammatory bowel disease (IBD) remains elusive. Accumulating
evidence suggests that the abnormality of innate and adaptive immunity responses plays an …

The function and role of the Th17/Treg cell balance in inflammatory bowel disease

J Yan, M Luo, Z Chen, B He - Journal of immunology research, 2020 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic, inflammatory, and autoimmune disorder. The
pathogenesis of IBD is not yet clear. Studies have shown that the imbalance between T …

The involvement of TH17 cells in the pathogenesis of IBD

P Jiang, C Zheng, Y Xiang, S Malik, D Su, G Xu… - Cytokine & growth factor …, 2023 - Elsevier
The pathogenesis of inflammatory bowel disease (IBD) is still unclear. Immune dysfunction
may play a key role in the pathogenesis of IBD, in which the role of CD4+ T helper (Th) cells …

Th17 cells in inflammatory bowel disease: cytokines, plasticity, and therapies

J Zhao, Q Lu, Y Liu, Z Shi, L Hu, Z Zeng… - Journal of …, 2021 - Wiley Online Library
Autoimmune diseases (such as rheumatoid arthritis, asthma, autoimmune bowel disease)
are a complex disease. Improper activation of the immune system or imbalance of immune …

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

N Eastaff-Leung, N Mabarrack, A Barbour… - Journal of clinical …, 2010 - Springer
Background Inflammatory bowel disease (IBD) is thought to result from an aberrant immune
response. Inflammation in IBD may be caused by the loss of homeostasis between CD4+ …