Iron deficiency and iron overload are the most prevalent and opposite forms of dysregulated
iron metabolism that affect approximately 30 percent of the world population, in particularly …

The maintenance of iron homeostasis is essential for proper cardiac function. A growing
body of evidence suggests that iron imbalance is the common denominator in many …

Iron is essential for many biological processes. Inadequate or excess amount of body iron
can result in various pathological consequences. The pathological roles of iron in …

Iron is an essential mineral required for a variety of vital biological functions. Despite being
vital for life, iron also has potentially toxic aspects. Iron has been investigated as a risk factor …

Coronary heart disease (CHD) is closely related to oxidative stress and inflammatory
response and is the most common cardiovascular disease (CVD). Iron is an essential …

Background: Cardiovascular disease (CVD) remains the leading cause of disease burden
worldwide. Ferroptosis, an iron-dependent form of programmed cell death, is characterized …

Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …

Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated
to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure …

Iron is an essential mineral participating in different functions of the organism under
physiological conditions. Numerous biological processes, such as oxygen and lipid …

Cell death is an important component of the pathophysiology of cardiovascular disease. An
understanding of how cardiomyocytes die, and why regeneration of cells in the heart is …