Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi

E Rampacci, ML Marenzoni, R Cannalire… - Journal of …, 2021 - academic.oup.com
Background This study introduces a newly created strain (Rhodococcus equi EtBr25) by
exposing R. equi ATCC 33701 to ethidium bromide (EtBr), a substrate for MDR transporters …

[HTML][HTML] Genotypic and phenotypic detection of efflux pump in Rhodococcus equi

LT Gressler, AC Vargas, MM Costa, L Pötter… - Brazilian Journal of …, 2014 - SciELO Brasil
The req_39680 gene, associated to a putative efflux system, was detected in 60%(54/90) of
R. equi isolates by PCR. The phenotypic expression of efflux mechanism was verified in …

[PDF][PDF] Antimicrobial resistance in Rhodococcus equi

A Cisek, M Rzewuska, L Witkowski… - Acta Biochimica …, 2014 - bibliotekanauki.pl
Rhodococcus equi is an important etiologic agent of respiratory-and non-respiratory tract
infections, diseases of animals and humans. Therapy includes the use of various group of …

MICs of 32 antimicrobial agents for Rhodococcus equi isolates of animal origin

A Riesenberg, AT Feßler, E Erol… - Journal of …, 2014 - academic.oup.com
Objectives The aim of this study was to determine the MICs of 32 antimicrobial agents for
200 isolates of Rhodococcus equi of animal origin by applying a recently described broth …

[HTML][HTML] Relationship between rifampicin resistance and RpoB substitutions of Rhodococcus equi strains isolated in France

S Petry, C Sévin, S Kozak, N Foucher, C Laugier… - Journal of Global …, 2020 - Elsevier
Objectives Study the rifampicin resistance of Rhodococcus equi strains isolated from French
horses over a 20-year period. Methods Rifampicin susceptibility tested by disc diffusion and …

Antimicrobial resistance spectrum conferred by pRErm46 of emerging macrolide (multidrug)-resistant Rhodococcus equi

E Erol, M Scortti, J Fortner, M Patel… - Journal of clinical …, 2021 - Am Soc Microbiol
Clonal multidrug resistance recently emerged in Rhodococcus equi, complicating the
therapeutic management of this difficult-to-treat animal-and human-pathogenic …

Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide

I Couto, SS Costa, M Viveiros… - Journal of …, 2008 - academic.oup.com
Objectives By adapting an antibiotic-susceptible Staphylococcus aureus strain to increasing
concentrations of ethidium bromide, a known substrate of efflux pumps (EPs), and by …

Novel transferable erm(46) determinant responsible for emerging macrolide resistance in Rhodococcus equi

E Anastasi, S Giguere, LJ Berghaus… - Journal of …, 2015 - academic.oup.com
Objectives The objective of this study was to identify the molecular mechanism of macrolide
resistance in the actinomycete Rhodococcus equi, a major equine pathogen and zoonotic …

Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen

SS Costa, M Viveiros, C Pomba… - Journal of Antimicrobial …, 2018 - academic.oup.com
Objectives To analyse the efflux-mediated response of Staphylococcus epidermidis to
ethidium bromide (EtBr), a substrate of multidrug efflux pumps (EPs). Methods The …

[HTML][HTML] Interplay Between the Phenotype and Genotype, and Efflux Pumps in Drug-Resistant Strains of Riemerella anatipestifer

Q Chen, X Gong, F Zheng, G Ji, S Li… - Frontiers in …, 2018 - frontiersin.org
The number of multidrug-resistant strains of Riemerella anatipestifer continues to increase,
and new strategies for the treatment of associated infections are necessary. Recently …