The nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE)
pathway is an important cell signaling mechanism in maintaining redox homeostasis in …

Cancer chemoprevention involves the application of natural or synthetic compounds to
reduce the risk of cancer development. One of the most effective strategies for preventing …

While functioning as a second messenger in the intracellular signaling, ROS can cause
oxidative stress when produced in excess or not neutralized/eliminated properly. Excessive …

BACKGROUND: One of the potential strategies for preventing cancers is using food-based
natural products to induce cytoprotective enzymes including phase II and antioxidative …

In response to oxidative stress, the transcription factor NF-E2-related factor 2 (Nrf2) controls
the fate of cells through transcriptional upregulation of antioxidant response element (ARE) …

Oxidative stress is caused by an imbalance of reactive oxygen species (ROS)/reactive
nitrogen species (RNS) and the antioxidative stress defense systems in cells. ROS/RNS or …

Cancer chemoprevention is a process of using either natural or synthetic compounds to
reduce the risk of developing cancer. Observations that NF-E2-related factor 2 (Nrf2) …

One of the most prominent strategies of cancer chemoprevention might be protecting cells or
tissues against various carcinogens and carcinogenic metabolites derived from exogenous …

Redox imbalance is a major contributor to the pathogenesis of melanoma and
nonmelanoma skin cancer. Activation of the nuclear factor E2–related factor 2 (Nrf2) …

The Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor regulating a
wide array of genes for antioxidant and detoxification enzymes in response to oxidative and …