GC–MS based metabolomics used for the identification of cancer volatile organic compounds as biomarkers

G Lubes, M Goodarzi - Journal of pharmaceutical and biomedical analysis, 2018 - Elsevier
A biomarker can be a metabolite, coming from a metabolic pathway or cell process, which
might be employed in the diagnostic of diseases, predict patient response towards chemical …

GC‐MS metabolomics‐based approach for the identification of a potential VOC‐biomarker panel in the urine of renal cell carcinoma patients

M Monteiro, N Moreira, J Pinto… - Journal of cellular …, 2017 - Wiley Online Library
The analysis of volatile organic compounds (VOCs) emanating from biological samples
appears as one of the most promising approaches in metabolomics for the study of …

Metabolomics in cancer biomarker discovery: current trends and future perspectives

EG Armitage, C Barbas - Journal of pharmaceutical and biomedical …, 2014 - Elsevier
Cancer is one of the most devastating human diseases that causes a vast number of
mortalities worldwide each year. Cancer research is one of the largest fields in the life …

Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

Determination of volatile products of human colon cell line metabolism by GC/MS analysis

D Zimmermann, M Hartmann, MP Moyer, J Nolte… - Metabolomics, 2007 - Springer
Colon cancer is one of the most reasons for cancer death worldwide. Thus, it is important to
find new prognostic and diagnostic marker, as well as to throw light on the special metabolic …

Applications of metabolomics in cancer studies

EG Armitage, M Ciborowski - Metabolomics: From fundamentals to clinical …, 2017 - Springer
Since the start of metabolomics as a field of research, the number of studies related to
cancer has grown to such an extent that cancer metabolomics now represents its own …

[HTML][HTML] Volatile metabolomic signature of human breast cancer cell lines

CL Silva, R Perestrelo, P Silva, H Tomás, JS Câmara - Scientific reports, 2017 - nature.com
Breast cancer (BC) remains the most prevalent oncologic pathology in women, causing
huge psychological, economic and social impacts on our society. Currently, the available …

Emerging field of metabolomics: big promise for cancer biomarker identification and drug discovery

S Patel, S Ahmed - Journal of pharmaceutical and biomedical analysis, 2015 - Elsevier
Most cancers are lethal and metabolic alterations are considered a hallmark of this deadly
disease. Genomics and proteomics have contributed vastly to understand cancer biology …

Metabolomics applications in precision medicine: an oncological perspective

L Puchades-Carrasco… - Current topics in …, 2017 - ingentaconnect.com
Nowadays, cancer therapy remains limited by the conventional one-size-fits-all approach. In
this context, treatment decisions are based on the clinical stage of disease but fail to …

Chemometrics in metabolomics—a review in human disease diagnosis

R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …