Pulmonary alveolar proteinosis

BC Trapnell, K Nakata, F Bonella, I Campo… - Nature Reviews …, 2019 - nature.com
Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by the accumulation of
alveolar surfactant and dysfunction of alveolar macrophages. PAP results in progressive …

The molecular basis of pulmonary alveolar proteinosis

B Carey, BC Trapnell - Clinical immunology, 2010 - Elsevier
Pulmonary alveolar proteinosis (PAP) comprises a heterogenous group of diseases
characterized by abnormal surfactant accumulation resulting in respiratory insufficiency, and …

Pulmonary alveolar proteinosis

OC Ioachimescu, MS Kavuru - Chronic respiratory disease, 2006 - journals.sagepub.com
Pulmonary alveolar proteinosis is a rare syndrome characterized by intra-alveolar
accumulation of surfactant components and cellular debris, with minimal interstitial …

Pulmonary alveolar proteinosis

R Borie, C Danel, MP Debray, C Taille… - European …, 2011 - Eur Respiratory Soc
Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease characterised by alveolar
accumulation of surfactant. It may result from mutations in surfactant proteins or granulocyte …

Pulmonary alveolar proteinosis in adults: pathophysiology and clinical approach

A Kumar, B Abdelmalak, Y Inoue… - The Lancet Respiratory …, 2018 - thelancet.com
Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease that results from the
accumulation of lipoproteinaceous material in the alveoli and alveolar macrophages due to …

Pulmonary alveolar proteinosis

A Khan, R Agarwal - Respiratory care, 2011 - rc.rcjournal.com
Pulmonary alveolar proteinosis is a rare but potentially treatable disease, characterized by
impaired surfactant metabolism that leads to accumulation in the alveoli of proteinaceous …

Autoantibodies against granulocyte macrophage colony–stimulating factor are diagnostic for pulmonary alveolar proteinosis

TL Bonfield, D Russell, S Burgess, A Malur… - American journal of …, 2002 - atsjournals.org
Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the accumulation of
phospholipids and surfactant proteins in the lung. The central role for granulocyte …

Pulmonary alveolar proteinosis

JJ Presneill, K Nakata, Y Inoue… - Clinics in chest …, 2004 - chestmed.theclinics.com
Pulmonary alveolar proteinosis (PAP)(also called alveolar proteinosis, alveolar
phospholipidosis, pulmonary alveolar lipoproteinosis, pulmonary alveolar …

Pulmonary alveolar proteinosis: progress in the first 44 years

JF Seymour, JJ Presneill - … journal of respiratory and critical care …, 2002 - atsjournals.org
Pulmonary alveolar proteinosis is a rare clinical syndrome that was first described in 1958.
Subsequently, over 240 case reports and small series have described at least 410 cases in …

[HTML][HTML] Prevalence and healthcare burden of pulmonary alveolar proteinosis

C McCarthy, R Avetisyan, BC Carey, C Chalk… - Orphanet Journal of …, 2018 - Springer
Pulmonary alveolar proteinosis (PAP) is a rare syndrome of alveolar surfactant
accumulation, resulting hypoxemic respiratory failure, and increased infection risk. Despite …