Efficacy of biologics for the treatment of periodontal infrabony defects: an American Academy of Periodontology best evidence systematic review and network meta …

L Tavelli, CY Chen, S Barootchi… - Journal of …, 2022 - Wiley Online Library
Background A large variety of biomaterials, biologics and membranes have been utilized in
the past 40 years for the regenerative treatment of periodontal infrabony defects. Biologic …

Periodontal regeneration–intrabony defects: a consensus report from the AAP Regeneration Workshop

MA Reynolds, RT Kao, PM Camargo… - Journal of …, 2015 - Wiley Online Library
Background: Treatment of intrabony defects is an important therapeutic goal of periodontal
therapy. The goal of this consensus report was to critically appraise the evidence for the …

Efficacy of adjunctive bioactive materials in the treatment of periodontal intrabony defects: a systematic review and meta‐analysis

S Zhou, C Sun, S Huang, X Wu, Y Zhao… - BioMed research …, 2018 - Wiley Online Library
Objectives. Lots of bioactive materials have been additionally applied for the treatment of
periodontal intrabony defect. However, there is dearth of studies to systematically evaluate …

Periodontal regeneration–intrabony defects: a systematic review from the AAP regeneration workshop

RT Kao, S Nares, MA Reynolds - Journal of periodontology, 2015 - Wiley Online Library
Background: Previous systematic reviews of periodontal regeneration with bone
replacement grafts and guided tissue regeneration (GTR) were defined as state of the art for …

Outcomes of regenerative treatment with rh PDGF‐BB and rh FGF‐2 for periodontal intra‐bony defects: a systematic review and meta‐analysis

V Khoshkam, HL Chan, GH Lin, J Mailoa… - Journal of Clinical …, 2015 - Wiley Online Library
Background The aim was to evaluate the effects of recombinant human platelet‐derived
growth factor‐BB (rh PDGF‐BB) and recombinant human fibroblast growth factor‐2 (rh FGF …

American Academy of Periodontology best evidence consensus statement on the use of biologics in clinical practice

G Avila‐Ortiz, J Ambruster, S Barootchi… - Journal of …, 2022 - Wiley Online Library
A biologic is a therapeutic agent with biological activity that is administered to achieve an
enhanced regenerative or reparative effect. The use of biologics has progressively become …

Systematic review and sequential network meta‐analysis on the efficacy of periodontal regenerative therapies

SJ Tsai, YW Ding, MC Shih… - Journal of Clinical …, 2020 - Wiley Online Library
Aims We aimed to update a previous network meta‐analysis comparing the efficacy of
periodontal regenerative therapies on the treatment of infrabony lesions. Materials and …

Which biomaterials may promote periodontal regeneration in intrabony periodontal defects? A systematic review of preclinical studies.

A Ivanovic, G Nikou, RJ Miron… - Quintessence …, 2014 - search.ebscohost.com
Objective: To systematically analyze the regenerative effect of the available biomaterials
either alone or in various combinations for the treatment of periodontal intrabony defects as …

Medium‐and long‐term clinical benefits of periodontal regenerative/reconstructive procedures in intrabony defects: Systematic review and network meta‐analysis of …

A Stavropoulos, K Bertl, LM Spineli… - Journal of clinical …, 2021 - Wiley Online Library
Background Systematic reviews have established the short‐term improvements of
periodontal regenerative/reconstructive procedures compared to conventional surgical …

Clinical outcomes with bioactive agents alone or in combination with grafting or guided tissue regeneration

L Trombelli, R Farina - Journal of clinical periodontology, 2008 - Wiley Online Library
Aim: The purpose of the present review was to determine the clinical effect of the use of
bioactive agents (BAs) for the treatment of intra‐osseous and furcation defects. Material and …