Objective Immune responses are important in dictating non-alcoholic steatohepatitis (NASH)
outcome. We previously reported that upregulation of hedgehog (Hh) and osteopontin …

Liver inflammation is greater in nonalcoholic steatohepatitis (NASH) than steatosis,
suggesting that immune responses contribute to nonalcoholic fatty liver disease (NAFLD) …

Nonalcoholic steatohepatitis (NASH) affects 3%‐5% of the US population, having severe
clinical complications to the development of fibrosis and end‐stage liver diseases, such as …

Growing evidence indicates that NF-κB (nuclear factor κB) activation contributes to the
pathogenesis of NASH (non-alcoholic steatohepatisis). Among the NF-κB subunits, p50/NF …

Nonalcoholic steatohepatitis (NASH) is a leading cause of cirrhosis. Recently, we showed
that NASH‐related cirrhosis is associated with Hedgehog (Hh) pathway activation. The gene …

Abstract Background & Aims Non‐alcoholic steatohepatitis (NASH) is a major cause of
chronic liver disease. The precise role of NK cells in the progression of NASH has yet to be …

Background & Aims Hepatic immune microenvironment plays a pivotal role in the
development of nonalcoholic steatohepatitis (NASH). However, the role of natural killer (NK) …

Nonalcoholic steatohepatitis (NASH), characterized by lipid deposits within hepatocytes
(steatosis), is associated with hepatic injury and inflammation and leads to the development …

Hepatic inflammation is a key pathologic feature of nonalcoholic steatohepatitis (NASH).
Natural killer T (NKT) cells and clusters of differentiation (CD) 8+ T‐cells are known to play …

Fibrosis is the major determinant of morbidity and mortality in patients with nonalcoholic
steatohepatitis (NASH) but has no approved pharmacotherapy in part because of …