CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro
There is increasing evidence that the expression of CD109, a GPI-anchored cell surface
protein is dysregulated in squamous cell carcinoma (SCC). However, the functional role of …
protein is dysregulated in squamous cell carcinoma (SCC). However, the functional role of …
Up‐regulation of CD109 expression is associated with carcinogenesis of the squamous epithelium of the oral cavity
S Hagiwara, Y Murakumo, T Sato, T Shigetomi… - Cancer …, 2008 - Wiley Online Library
CD109 is a glycosylphosphatidylinositol (GPI)–anchored glycoprotein whose expression is
up‐regulated in squamous cell carcinomas (SCCs) of the lung, esophagus, and uterus. The …
up‐regulated in squamous cell carcinomas (SCCs) of the lung, esophagus, and uterus. The …
CD109 and squamous cell carcinoma
Squamous cell carcinoma (SCC) is well-known for its high rate of metastasis with poor
prognosis. CD109 is a glycosylphosphatidylinositol-anchored cell-surface glycoprotein …
prognosis. CD109 is a glycosylphosphatidylinositol-anchored cell-surface glycoprotein …
CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and STAT3 signalling in cervical squamous cell carcinoma
XT Mo, THY Leung, HWM Tang, MKY Siu… - British Journal of …, 2020 - nature.com
Background CD109 was involved in the tumorigenesis and progression of various cancers
via TGF-β1 signalling and STAT3 activation. As CD109 is strongly expressed in cervical …
via TGF-β1 signalling and STAT3 activation. As CD109 is strongly expressed in cervical …
CD109 is a critical determinant of EGFR expression and signaling, and tumorigenicity in squamous cell carcinoma cells
S Zhou, A Hassan, T Kungyal, S Tabariès, JLRG Luna… - Cancers, 2022 - mdpi.com
Simple Summary Squamous cell carcinoma is a type of cancer resulting from cancer of the
squamous cells that line some organs of the body such as the skin, lungs, and vulva. It is …
squamous cells that line some organs of the body such as the skin, lungs, and vulva. It is …
CD109: a multifunctional GPI‐anchored protein with key roles in tumor progression and physiological homeostasis
S Mii, A Enomoto, Y Shiraki, T Taki… - Pathology …, 2019 - Wiley Online Library
CD109 is a glycosylphosphatidylinositol‐anchored glycoprotein and a member of the α2‐
macroglobulin/C3, C4, C5 family of thioester‐containing proteins first identified as being …
macroglobulin/C3, C4, C5 family of thioester‐containing proteins first identified as being …
[HTML][HTML] CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells
JM Zhang, Y Murakumo, S Hagiwara, P Jiang… - Biochemical and …, 2015 - Elsevier
CD109 is a glycosylphosphatidylinositol-anchored cell surface protein that is frequently
detected in squamous cell carcinomas. CD109 is a negative regulator of TGF-β1 signaling in …
detected in squamous cell carcinomas. CD109 is a negative regulator of TGF-β1 signaling in …
[HTML][HTML] Suppression of skin tumorigenesis in CD109-deficient mice
M Sunagawa, S Mii, A Enomoto, T Kato, Y Murakumo… - Oncotarget, 2016 - ncbi.nlm.nih.gov
CD109 is a glycosylphosphatidylinositol-anchored glycoprotein that is highly expressed in
several types of human cancers, particularly squamous cell carcinomas. We previously …
several types of human cancers, particularly squamous cell carcinomas. We previously …
CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF‐β signaling
Stromal invasion is considered an important prognostic factor in patients with lung
adenocarcinoma. The mechanisms underlying the formation of tumor stroma and stromal …
adenocarcinoma. The mechanisms underlying the formation of tumor stroma and stromal …
[HTML][HTML] CD109 expression is upregulated in penile squamous cell carcinoma
F Dong, J Wang, Y Xu, Z Cheng, X Chen… - Oncology …, 2017 - spandidos-publications.com
Cluster of differentiation (CD) 109 is a glycosylphosphatidylinositol‑anchored cell surface
glycoprotein and a co‑receptor for transforming growth factor β. The expression of CD109 …
glycoprotein and a co‑receptor for transforming growth factor β. The expression of CD109 …