[HTML][HTML] Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design

SAA Kooijmans, OG de Jong, RM Schiffelers - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …

Functionalized extracellular vesicles as advanced therapeutic nanodelivery systems

M Lu, H Xing, Z Xun, T Yang, X Zhao, C Cai… - European Journal of …, 2018 - Elsevier
Extracellular vesicles (EVs) are membrane enclosed vesicles that are shed by almost all cell
types, and play a fundamental role in cell-to-cell communication. The discovery that EVs are …

[HTML][HTML] Converting extracellular vesicles into nanomedicine: loading and unloading of cargo

BS Joshi, D Ortiz, IS Zuhorn - Materials Today Nano, 2021 - Elsevier
Extracellular vesicles (EVs) are membranous containers that are secreted by multiple cell
types and actively transport biomolecules such as lipids, proteins, and nucleic acids to …

Extracellular vesicles for drug delivery

P Vader, EA Mol, G Pasterkamp… - Advanced drug delivery …, 2016 - Elsevier
Extracellular vesicles (EVs) are cell-derived membrane vesicles, and represent an
endogenous mechanism for intercellular communication. Since the discovery that EVs are …

[HTML][HTML] Extracellular vesicles as drug delivery systems: Why and how?

OM Elsharkasy, JZ Nordin, DW Hagey… - Advanced drug delivery …, 2020 - Elsevier
Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …

Extracellular vesicles as an efficient and versatile system for drug delivery

XTT Dang, JM Kavishka, DX Zhang, M Pirisinu, MTN Le - Cells, 2020 - mdpi.com
Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …

Extracellular vesicles: unique intercellular delivery vehicles

SLN Maas, XO Breakefield, AM Weaver - Trends in cell biology, 2017 - cell.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …

Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading

J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …

Exploiting the natural properties of extracellular vesicles in targeted delivery towards specific cells and tissues

P Lara, AB Chan, LJ Cruz, AFG Quest, MJ Kogan - Pharmaceutics, 2020 - mdpi.com
Extracellular vesicles (EVs) are important mediators of intercellular communication that
participate in many physiological/pathological processes. As such, EVs have unique …

[HTML][HTML] Engineering of extracellular vesicles as drug delivery vehicles

SM Kim, HS Kim - Stem cell investigation, 2017 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are secreted membrane-enclosed nano-sized particles (40–
1,000 nm) that deliver biological information between cells. The molecular composition of …