Aberrant protein glycosylation is known to be associated with the development of cancers.
The aberrant glycans are produced by the combined actions of changed glycosylation …

Glycosylation is recognized as one of the most common modifications on proteins. Recent
studies have shown that aberrant expression of α (1, 6) fucosyltransferase (FUT8), which …

The up-regulation of fucosyltransferase 8 (FUT8), the only enzyme catalyzing α1, 6-
fucosylation in mammals, has been observed in several malignant cancers including liver …

Background Pancreatic carcinoma is one of the deadliest malignant diseases, in which the
increased expression of α1, 6-fucosyltransferase (FUT8), a sole enzyme responsible for …

Abstract Objecitive: Fucosyltransferase 8 (FUT8), the only enzyme responsible for the core
α1, 6-fucosylation of asparagine-linked oligosaccharides of glycoproteins, is a vital enzyme …

Altered glycosylation is a universal feature of cancer cells and altered glycans can help
cancer cells escape immune surveillance, facilitate tumor invasion, and increase …

Purpose Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic
cancer. It is an aggressive malignancy associated with poor prognosis because of …

BACKGROUND Protein glycosylation is a common posttranslational modification and glycan
structural changes have been observed in several malignancies including prostate cancer …

The aim of this study was to compare the expression of fucosyltransferase 8 (FUT8) in breast
cancer tissue and to investigate the relationship between this marker with tumor progression …

Fucosyltransferases (FUTs) are critical for glycoproteins and glycolipid chains and serve an
important role in the adhesive interaction between selectins and their ligands, which …