Cancer and neurological disease afflict millions of people in the United States and
worldwide. In addition to the heavy toll they take on society, these diseases have …

Non-invasive energy metabolism measurements in brain tumors in vivo are now performed
widely as molecular imaging by positron emission tomography. This capability has …

Many cancer chemotherapeutics target DNA, which makes them vulnerable to repair by
innate mechanisms the cell has evolved to ward off endogenous and exogenous DNA …

Molecular Imaging is very attractive to both physicians and researchers, as it allows
investigation into more basic aspects of disease than traditional modalities. In both research …

Anatomical imaging has been the conventional paradigm for diagnosis since the advent of
radiography a century ago. Computed tomography (CT), magnetic resonance (MR), and …

Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

Optical imaging using fluorescent probes, along with related biomedical imaging
technologies such as PET, SPECT, MRI and bioluminescence, represents a return to in situ …

In the past decade, our increased elucidation of the molecular basis of cancer has led to the
development of novel targeted strategies for specific inhibition of cancer signaling pathways …

In this second article, we review the various strategies and applications that make use of
reporter genes for molecular imaging of the brain in living subjects. These approaches are …

Fluorescence imaging is becoming an important diagnostic method in medicine. Advances
in the quantum yields and properties of fluorophores combined with better biologic targeting …