Vitamin D and the immune system: beyond rickets

MA O'Brien, MW Jackson - The Veterinary Journal, 2012 - Elsevier
In addition to its essential role in calcium homeostasis and bone metabolism, vitamin D has
a diverse range of biological actions, including induction of cell differentiation, inhibition of …

Vitamin D metabolism and rickets in domestic animals: a review

KE Dittmer, KG Thompson - Veterinary Pathology, 2011 - journals.sagepub.com
Rickets and osteomalacia are increasing in prevalence in people because of cultural
practices, breast-feeding, decreased sun exposure, and increased sunscreen usage …

Vitamin D effectiveness and pathology in humans and domestic animals

HKM Alabada, WMM Saleh - Multidisciplinary Reviews, 2020 - malque.pub
Vitamin D is a fat-soluble vitamin that involved mainly for intestinal absorption of calcium
with the regulation of calcium/phosphorus hemostasis, bone formation and remodeling, and …

Vitamin D metabolism in dogs and cats and its relation to diseases not associated with bone metabolism

RVA Zafalon, LW Risolia, V Pedrinelli… - Journal of animal …, 2020 - Wiley Online Library
Due to the presence of receptors in the cells of numerous body tissues, vitamin D is
associated with several physiological functions that go beyond calcium and phosphorus …

Current perspectives on vitamin D, immune system, and chronic diseases

MC Borges, LA Martini, MM Rogero - Nutrition, 2011 - Elsevier
Accumulating data support that vitamin D possesses several biological and molecular
actions apart from its role in calcium homeostasis. Immune cells express vitamin D receptor …

The immunological implication of the new vitamin D metabolism

G Bivona, L Agnello, M Ciaccio - Central European Journal of …, 2018 - termedia.pl
Abstract vitamin D is a neuro-hormone regulating calcium-phosphate homeostasis, cell
proliferation, and immunomodulation. exogenous and endogenous vitamin D is inactive …

An update on vitamin D and human immunity

M Hewison - Clinical endocrinology, 2012 - Wiley Online Library
In the last 5 years, there has been a remarkable change in our understanding of the health
benefits of vitamin D. The classical actions of vitamin D as a determinant of mineral …

Regulation of immune function by vitamin D and its use in diseases of immunity

AS Vanherwegen, C Gysemans… - … and Metabolism Clinics, 2017 - endo.theclinics.com
The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …

Vitamin D: nutrient, hormone, and immunomodulator

F Sassi, C Tamone, P D'Amelio - Nutrients, 2018 - mdpi.com
The classical functions of vitamin D are to regulate calcium-phosphorus homeostasis and
control bone metabolism. However, vitamin D deficiency has been reported in several …

Beyond the skeleton: the role of vitamin D in companion animal health

RJ Mellanby - Journal of Small Animal Practice, 2016 - Wiley Online Library
While the role of vitamin D in the maintenance of skeletal health has been well‐established
for many years, the discovery that many non‐skeletal tissues express the vitamin D receptor …