The pimple sign of progressive supranuclear palsy syndrome

H Botha, JL Whitwell, A Madhaven, ML Senjem… - Parkinsonism & Related …, 2014 - Elsevier
Background Some patients with progressive supranuclear palsy syndrome (PSPS)
demonstrate a focal area of midbrain hypometabolism on FDG-PET scans which we call the …

Midbrain atrophy is not a biomarker of progressive supranuclear palsy pathology

JL Whitwell, CR Jack Jr, JE Parisi… - European journal of …, 2013 - Wiley Online Library
Background and purpose Midbrain atrophy is a characteristic feature of progressive
supranuclear palsy (PSP), although it is unclear whether it is associated with the PSP …

Assessment of midbrain atrophy in patients with progressive supranuclear palsy with routine magnetic resonance imaging

M Cosottini, R Ceravolo, L Faggioni… - Acta neurologica …, 2007 - Wiley Online Library
Objectives–To assess midbrain atrophy through morphometric (linear, surface and
volumetric) measurements in patients with clinically diagnosed progressive supranuclear …

Beyond the midbrain atrophy: wide spectrum of structural MRI finding in cases of pathologically proven progressive supranuclear palsy

K Sakurai, AM Tokumaru, K Shimoji, S Murayama… - Neuroradiology, 2017 - Springer
Purpose Recently, it has been recognized that pathologically proven progressive
supranuclear palsy (PSP) cases are classified into various clinical subtypes with non …

MR imaging of brainstem atrophy in progressive supranuclear palsy

J Slowinski, A Imamura, RJ Uitti, RA Pooley… - Journal of …, 2008 - Springer
Background To enhance the sensitivity and specificity of the clinical diagnosis of progressive
supranuclear palsy (PSP), neuroradiological parameters established in pathologically …

Frontal hypometabolism in the diagnosis of progressive supranuclear palsy clinical variants

JA Black, NTT Pham, F Ali, MM Machulda, VJ Lowe… - Journal of …, 2024 - Springer
Objective Frontal hypometabolism on FDG-PET is observed in progressive supranuclear
palsy (PSP), although it is unclear whether it is a feature of all PSP clinical variants and …

The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy

LA Massey, HR Jäger, DC Paviour, SS O'Sullivan… - Neurology, 2013 - AAN Enterprises
Objectives: MRI-based measurements used to diagnose progressive supranuclear palsy
(PSP) typically lack pathologic verification and are not easy to use routinely. We aimed to …

New and reliable MRI diagnosis for progressive supranuclear palsy

H Oba, A Yagishita, H Terada, AJ Barkovich, K Kutomi… - Neurology, 2005 - AAN Enterprises
Objective: To evaluate the area of the midbrain and pons on mid-sagittal MRI in patients with
progressive supranuclear palsy (PSP), Parkinson disease (PD), and multiple-system atrophy …

Magnetic resonance imaging-based volumetry differentiates progressive supranuclear palsy from corticobasal degeneration

K Gröschel, TK Hauser, A Luft, N Patronas, J Dichgans… - Neuroimage, 2004 - Elsevier
Because there are no biological markers for the clinical diagnosis of progressive
supranuclear palsy (PSP) and corticobasal degeneration (CBD), we established a …

Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy

ED Driver-Dunckley, N Zhang… - … of Neuropathology & …, 2023 - academic.oup.com
The objective of this study was to determine the prevalence, incidence, and clinical
diagnostic accuracy for neuropathologically diagnosed progressive supranuclear palsy …