[HTML][HTML] A randomized trial of topical fibrinogen-depleted human platelet lysate treatment of dry eye secondary to chronic graft-versus-host disease

A Sugar, M Hussain, W Chamberlain, R Dana… - Ophthalmology …, 2022 - Elsevier
Purpose The purpose of the study was to evaluate, as a pilot trial, safety and tolerability of
CAM-101 10% and 30% topical ophthalmic fibrinogen-depleted human platelet lysate (FD …

Long-term safety and efficacy of autologous platelet lysate drops for treatment of ocular GvHD

S Pezzotta, C Del Fante, L Scudeller… - Bone marrow …, 2017 - nature.com
Current ocular GvHD (oGvHD) treatments are suboptimal. We investigated the safety and
efficacy of long-term continuous treatment with autologous platelet lysate (PL) drops in …

Treatment of dry eye disease with autologous platelet-rich plasma: a prospective, interventional, non-randomized study

JL Alio, AE Rodriguez, R Ferreira-Oliveira… - Ophthalmology and …, 2017 - Springer
Introduction The objective of this study was to evaluate the use of autologous platelet-rich
plasma (PRP) eye drops as monotherapy for the treatment of moderate to severe cases of …

Effect of autologous platelet-rich plasma eye drops in the treatment of dry eye disease (DED)

JB Nadelmann, VY Bunya, GS Ying… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: Platelet rich plasma (PRP) is an autologous preparation that concentrates platelets
in a small volume of plasma that has been used to treat ocular surface diseases. The …

[HTML][HTML] A single-center pilot prospective study of topical application of platelet-derived eye drops for patients with ocular chronic graft-versus-host disease

F Zallio, L Mazzucco, F Monaco, MR Astori… - Biology of Blood and …, 2016 - Elsevier
Ocular involvement of chronic graft-versus-host disease (cGVHD) is a complication that
occurs in up to 60% of patients after allogeneic hematopoietic stem cell transplantation …

Platelet-rich plasma lysate for treatment of eye surface diseases

L Merolle, B Iotti, P Berni, E Bedeschi, K Boito… - JoVE (Journal of …, 2022 - jove.com
Various ocular surface diseases are treated with blood-derived eye drops. Their use has
been introduced in clinical practice because of their metabolite and growth factor content …

Autologous serum therapy of the ocular surface with novel delivery by platelet concentrate gel

BH Koffler - The ocular surface, 2006 - Elsevier
Application of autologous serum to treat a multitude of ocular surface diseases and
conditions is a relatively new technique that has gained popularity over the past 10 years …

Use of autologous platelet-rich plasma in the treatment of dormant corneal ulcers

JL Alio, M Abad, A Artola, JL Rodriguez-Prats, S Pastor… - Ophthalmology, 2007 - Elsevier
PURPOSE: To investigate the potential role of autologous platelet-rich plasma in promoting
healing in dormant corneal ulcers. DESIGN: Prospective, consecutive, interventional …

Autologous platelet lysate for treatment of refractory ocular GVHD

S Pezzotta, C Del Fante, L Scudeller… - Bone Marrow …, 2012 - nature.com
Current treatment of ocular GVHD (oGVHD), represented by systemic immunosuppressive
regimens and local therapies (mainly artificial tears and corticosteroids), gives unsatisfactory …

Platelet-rich plasma for treating dry eye disease–A systematic review and meta-analysis

PK Akowuah, CJ Obinwanne, E Owusu… - Contact Lens and …, 2023 - Elsevier
Purpose Dry eye disease has public health and economic significance. Platelet-rich plasma
is rich in anti-inflammatory agents and growth factors, both beneficial for ocular surface …