Abstract Background Knee Osteoarthritis (KOA) is a heterogeneous pathology characterized
by a complex and multifactorial nature. It has been hypothesised that these differences are …

Objectives The existence of phenotypes has been hypothesized to explain the large
heterogeneity characterizing the knee osteoarthritis. In a previous systematic review of the …

Objective To systematically review the literature for studies investigating knee osteoarthritis
(OA) phenotypes to examine what OA characteristics are relevant for phenotyping. Methods …

Objective To identify and validate previously established phenotypes of knee osteoarthritis
(OA) based on similarities in clinical patient characteristics. Methods Knee OA patients (N …

Objective To identify subgroups or phenotypes of knee osteoarthritis (OA) patients based on
similarities of clinically relevant patient characteristics, and to compare clinical outcomes of …

Objective. OA is suspected to be a collection of distinct subtypes, each with different
aetiology and clinical characteristics. We aimed to explore the existence of different …

Objective To systematically summarize the literature on the course of pain in patients with
knee osteoarthritis (OA), prognostic factors that predict deterioration of pain, the course of …

Introduction Osteoarthritis (OA) is considered to be a multifactorial and polygenic disease
and diagnosis is mainly clinical and radiological. Correlation between radiographic data and …

Objective Knee osteoarthritis (OA) is a broadly applied diagnosis that may describe multiple
subtypes of pain. The purpose of this study was to identify phenotypes of knee OA, using …

Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases
rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and …