Complement system aberrations have been identified as pathophysiological mechanisms in
a number of diseases and pathological conditions either directly or indirectly. Examples of …

Aberrations in the complement system have been shown to be direct or indirect
pathophysiological mechanisms in a number of diseases and pathological conditions such …

In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and
C4, has significantly enhanced our understanding of the disease process. Such expanded …

Complement immunobiology, and with it complement analysis, has undergone a
renaissance in the past decade. Classically, complement analysis was limited number of …

Complement not only plays a key role in host microbial defense but also modulates the
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …

In recent years, progress in the delineation of reaction mechanisms of the complement
system greatly stimulated studies on the possible significance of complement in clinical …

The complement system is an ancient and evolutionary conserved element of the innate
immune mechanism. It comprises of more than 20 serum proteins most of which are …

Complement deficiencies are probably vastly under-diagnosed within clinical medicine.
Judging from a Swedish study of C2 deficiency, a deficiency with an estimated prevalence of …

Background The complement system is an essential component of our innate defense and
plays a vital role in the pathogenesis of many diseases. Assessment of complement …

Complement deficient cases reported in the second half of the last century have been of
great help in defining the role of complement in host defence. Surveys of the deficient …