[HTML][HTML] Biotransformations utilizing β-oxidation cycle reactions in the synthesis of natural compounds and medicines

A Œwizdor, A Panek, N Milecka-Tronina… - International Journal of …, 2012 - mdpi.com
β-Oxidation cycle reactions, which are key stages in the metabolism of fatty acids in
eucaryotic cells and in processes with a significant role in the degradation of acids used by …

Biotransformation of non-natural compounds: State of the art and future development

K Faber - Pure and applied chemistry, 1997 - degruyter.com
BIOTRANSFORMATIONS OF NON-NATURAL COMPOUNDS: STATE OF THE ART AND
FUTURE DEVELOPMENT Page 1 Pure &App/. Chern., Vol. 69, No. 8, pp. 1613-1632, 1997 …

Tools and ingredients for the biocatalytic synthesis of metabolites

R Wohlgemuth - Biotechnology Journal, 2009 - Wiley Online Library
Metabolic networks have been an interesting starting point not only for the design of
synthetic routes in a similar sequence of reactions, eg, in biomimetic syntheses, but also for …

Biotransformation: a green and efficient way of antioxidant synthesis

S Zafar, R Ahmed, R Khan - Free Radical Research, 2016 - Taylor & Francis
Antioxidant compounds play a vital role in human physiology. They prevent the oxidation of
biomolecules by scavenging free radicals produced during physiochemical processes …

[HTML][HTML] Plant products for pharmacology: application of enzymes in their transformations

M Zarevúcka, Z Wimmer - International journal of molecular sciences, 2008 - mdpi.com
Different plant products have been subjected to detailed investigations due to their
increasing importance for improving human health. Plants are sources of many groups of …

Metabolic engineering and directed evolution for the production of pharmaceuticals

M Chartrain, PM Salmon, DK Robinson… - Current Opinion in …, 2000 - Elsevier
The tools of metabolic and enzyme engineering have been well developed in academic
laboratories and are now being applied for the optimization of biocatalysts used in the …

Biocatalysis in pharmaceutical preparation and alteration

B Wilkinson, BO Bachmann - Current opinion in chemical biology, 2006 - Elsevier
The term 'synthetic biology'is being used with increasing frequency to describe the
biocatalytic generation of small molecules, either via stepwise biotransformation or …

Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering

A Kirschning, F Taft, T Knobloch - Organic & biomolecular chemistry, 2007 - pubs.rsc.org
Secondary metabolites are an extremely diverse and important group of natural products
with industrial and biomedical implications. Advances in metabolic engineering of both …

[HTML][HTML] Complexity reduction and opportunities in the design, integration and intensification of biocatalytic processes for metabolite synthesis

R Wohlgemuth, J Littlechild - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The biosynthesis of metabolites from available starting materials is becoming an ever
important area due to the increasing demands within the life science research area. Access …

Horizons of systems biocatalysis and renaissance of metabolite synthesis

R Wohlgemuth - biotechnology Journal, 2018 - Wiley Online Library
The small molecule domain of biological cellular systems is closely related to the synthesis
and breakdown of larger molecules such as DNA, RNA, proteins, or polysaccharides …