Identification of epigenetic dysregulation gene markers and immune landscape in kidney renal clear cell carcinoma by comprehensive genomic analysis

L Xie, S Wu, R He, S Li, X Lai, Z Wang - Frontiers in Immunology, 2022 - frontiersin.org
Kidney cancer is one the most lethal cancers of the urinary system, but current treatments
are limited and its prognosis is poor. This study focused on kidney renal clear cell carcinoma …

Construction and validation of risk model of EMT‐related prognostic genes for kidney renal clear cell carcinoma

LL Wu, SF Yuan, QY Lin, GM Chen… - The Journal of Gene …, 2023 - Wiley Online Library
Background Kidney renal clear cell carcinoma (KIRC) is a prevalent type of urological
malignancy. The present study aimed to predict biomarkers for KIRC. Methods We collected …

Comprehensive characterization of immune-and inflammation-associated biomarkers based on multi-omics integration in kidney renal clear cell carcinoma

E Zhao, L Li, W Zhang, W Wang, Y Chan… - Journal of Translational …, 2019 - Springer
Background Kidney renal clear cell carcinoma (KIRC) is the most common type of kidney
cancer in adults, and it is responsible for approximately 90–95% of cases. Although …

Gene set enrichment analysis identifies immune subtypes of kidney renal clear cell carcinoma with significantly different molecular and clinical properties

Z Chen, W Cao, J Luo, Z Abdelrahman, Q Lu… - Frontiers in …, 2023 - frontiersin.org
Background Kidney renal clear cell carcinoma (KIRC) is the most prevalent renal
malignancy, marked by a high abundance of tumor-infiltrating lymphocytes (TILs) and an …

Identification of Pathologic Grading‐Related Genes Associated with Kidney Renal Clear Cell Carcinoma

W Xiong, J Zhong, Y Li, X Li, L Wu… - Journal of Immunology …, 2022 - Wiley Online Library
Background. Renal epithelium lesions can cause renal cell carcinoma. This kind of tumor is
common among all renal cancers with poor prognosis, of which more than 70% belong to …

[HTML][HTML] The renal clear cell carcinoma immune landscape

OA Saad, WT Li, AR Krishnan, GC Nguyen, JP Lopez… - Neoplasia, 2022 - Elsevier
A comprehensive evaluation of the clear cell renal cell carcinoma (ccRCC) immune
landscape was found using 584 RNA-sequencing datasets from The Cancer Genome Atlas …

[HTML][HTML] Identification of a novel immune-related prognostic biomarker and small-molecule drugs in clear cell renal cell carcinoma (ccRCC) by a merged microarray …

GF Xiao, X Yan, Z Chen, RJ Zhang, TZ Liu… - Frontiers in …, 2020 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is one of the most common histological subtypes of
renal cancer, with a poor prognosis. Our study aimed to identify a biomarker that is …

Integrative epigenome-transcriptome analysis unravels cancer-specific over-expressed genes potentially regulating immune microenvironment in clear cell renal cell …

N Gadewal, A Natu, S Sen, S Rauniyar… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abstract Background Clear cell Renal Cell Carcinoma (ccRCC) is the frequently diagnosed
histological life-threatening tumor subtype in the urinary system. Integrating multi-omics data …

[HTML][HTML] Functional assessment of four novel immune-related biomarkers in the pathogenesis of clear cell renal cell carcinoma

D Lv, X Wu, M Wang, W Chen, S Yang, Y Liu… - Frontiers in Cell and …, 2021 - frontiersin.org
Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal
cell carcinoma whose pathogenesis is not well understood. We aimed at identifying novel …

[HTML][HTML] External validation of the prognostic value of an immune-associated gene panel for clear cell renal cell carcinomas

Z Xie, L Wu, S Hua, Y Zhang, F Shi, M Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
Clear cell renal cell carcinomas (ccRCCs) are highly immune infiltrates, and many of them
respond to immunotherapy with checkpoint inhibitors including anti-PD-L1 or anti-PD1 …