Background Integrin alpha-V-beta-3 (αvβ3) pathway is involved in intraplaque angiogenesis
and inflammation and represents a promising target for molecular imaging in cardiovascular …

Objective In this study, the feasibility and kinetic characteristics of the 68 Ga-NOTA-RGD, a
recently developed RGD peptide agent, were investigated for atherosclerosis imaging in …

Background Expression of α v β 3 integrin has been proposed as a marker for
atherosclerotic lesion inflammation. We studied whether diet intervention reduces uptake of …

Background—18F-Galacto-RGD is a positron emission tomography (PET) tracer binding to
αvβ3 integrin that is expressed by macrophages and endothelial cells in atherosclerotic …

Background Inflammation and angiogenesis play an important role in atherosclerotic plaque
rupture. Therefore, molecular imaging of these processes could be used for determination of …

Objectives: The goal of this study was to evaluate the feasibility of [18F] Galacto-RGD
positron emission tomography (PET)/computed tomography (CT) imaging of αvβ3 …

Rationale: The high expression of Galectin-3 (Gal3) in macrophages of atherosclerotic
plaques suggests its participation in atherosclerosis pathogenesis, and raises the possibility …

Angiogenesis is crucial in tissue repair and prevents scar tissue formation following an
ischemic event such as myocardial infarction. The ischemia induces formation of new …

Background Angiogenesis has increasingly been a target for imaging and treatment over the
last decade. The integrin αvβ3 is highly expressed in cells during angiogenesis and are …

Angiogenesis is part of the healing process following an ischemic injury and is vital for the
post-ischemic repair of the myocardium. Therefore, it is of particular interest to be able to …