Validation of the VirCapSeq-VERT system for differential diagnosis, detection, and surveillance of viral infections
There is a need in clinical microbiology and public health for assays that enable sensitive
and rapid detection of infectious agents. Next Generation Sequencing (NGS) is increasingly …
and rapid detection of infectious agents. Next Generation Sequencing (NGS) is increasingly …
Target-independent high-throughput sequencing methods provide evidence that already known human viral pathogens play a main role in respiratory infections with …
U Pérez-Sautu, MR Wiley… - Emerging Microbes & …, 2019 - Taylor & Francis
Despite the advanced PCR-based assays available, a fraction of the pediatric respiratory
infections remain unexplained every epidemic season, and there is a perception that novel …
infections remain unexplained every epidemic season, and there is a perception that novel …
Managing viral emerging infectious diseases via Current and future molecular diagnostics
M Altindiş, EP Kahraman Kilbaş - Diagnostics, 2023 - mdpi.com
Emerging viral infectious diseases have been a constant threat to global public health in
recent times. In managing these diseases, molecular diagnostics has played a critical role …
recent times. In managing these diseases, molecular diagnostics has played a critical role …
Current trends in diagnostics of viral infections of unknown etiology
Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …
Agnostic sequencing for detection of viral pathogens
NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …
detect and analyze microbial genomes and has yielded novel molecular approaches for …
DisCVR: Rapid viral diagnosis from high-throughput sequencing data
M Maabar, AJ Davison, M Vučak, F Thorburn… - Virus …, 2019 - academic.oup.com
High-throughput sequencing (HTS) enables most pathogens in a clinical sample to be
detected from a single analysis, thereby providing novel opportunities for diagnosis …
detected from a single analysis, thereby providing novel opportunities for diagnosis …
Application of next generation sequencing for the detection of human viral pathogens in clinical specimens
J Parker, J Chen - Journal of Clinical Virology, 2017 - Elsevier
Background Next generation sequencing (NGS) is a new technology that can be used for
broad detection of infectious pathogens and is rapidly becoming an essential platform in …
broad detection of infectious pathogens and is rapidly becoming an essential platform in …
Unbiased metagenomic sequencing complements specific routine diagnostic methods and increases chances to detect rare viral strains
DW Lewandowska, O Zagordi, A Zbinden… - … and infectious disease, 2015 - Elsevier
Multiplex PCR assays for respiratory viruses are widely used in routine diagnostics, as they
are highly sensitive, rapid, and cost effective. However, depending on the assay system …
are highly sensitive, rapid, and cost effective. However, depending on the assay system …
Targeted sequencing of respiratory viruses in clinical specimens for pathogen identification and genome-wide analysis
Y Yang, SD Walls, SM Gross, GP Schroth… - The Human Virome …, 2018 - Springer
A large number of viruses can individually and concurrently cause various respiratory
illnesses. Metagenomic sequencing using next-generation sequencing (NGS) technology is …
illnesses. Metagenomic sequencing using next-generation sequencing (NGS) technology is …
[HTML][HTML] The use of next generation sequencing in the diagnosis and typing of respiratory infections
F Thorburn, S Bennett, S Modha, D Murdoch… - Journal of Clinical …, 2015 - Elsevier
Background Molecular assays are the gold standard methods used to diagnose viral
respiratory pathogens. Pitfalls associated with this technique include limits to the number of …
respiratory pathogens. Pitfalls associated with this technique include limits to the number of …