With the advent of long-read sequencing, previously unresolvable genomic elements are
being revisited in an effort to generate fully complete reference genomes. One such element …

Ribosomal RNA gene repeats (rDNA) encode ribosomal RNA, a major component of
ribosomes. Ribosome biogenesis is central to cellular metabolic regulation, and several …

Despite the key role of the human ribosome in protein biosynthesis, little is known about the
extent of sequence variation in ribosomal DNA (rDNA) or its pre-rRNA and rRNA products …

Ribosomal DNA (rDNA) sequences are effectively used to infer the phylogenetic
relationships among organisms at all taxonomic ranks (Avise, 2004). Among eukaryotes …

Nuclear ribosomal RNA (rRNA) genes represent the oldest repetitive fraction universal to all
eukaryotic genomes. Their deeply anchored universality and omnipresence during …

The classical model of concerted evolution states that hundreds to thousands of ribosomal
DNA (rDNA) units undergo homogenization, making the multiple copies of the individual …

A call for direct sequencing of full-length RNAs to identify all modifications | Nature Genetics
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Ribosomes are large, multi-subunit ribonucleoprotein complexes, essential for protein
synthesis. To meet the high cellular demand for ribosomes, all eukaryotes have numerous …

Ribosomal RNAs (rRNAs) account for> 60% of all RNAs in eukaryotic cells and are encoded
in the ribosomal DNA (rDNA) arrays. The rRNAs are produced from two sets of loci: the 5S …

The evolution of the multi-copy family of ribosomal RNA (rRNA) genes is unique in regard to
its genetics and genome evolution. Paradoxically, rRNA genes are highly homogenized …