Rosmarinic acid ameliorates acute liver damage and fibrogenesis in carbon tetrachloride-intoxicated mice

R Domitrović, M Škoda, VV Marchesi… - Food and chemical …, 2013 - Elsevier
The aim of this study was to investigate the therapeutic potential of rosmarinic acid (RA), a
natural phenolic, in the treatment of acute liver toxicity. RA at 10, 25 and 50mg/kg was …

[HTML][HTML] Rosmarinic acid exerts anti-inflammatory effect and relieves oxidative stress via Nrf2 activation in carbon tetrachloride-induced liver damage

Y Lu, Y Hong, T Zhang, Y Chen, Z Wei… - Food & Nutrition …, 2022 - ncbi.nlm.nih.gov
Background Rosmarinic acid (RA) has biological and pharmaceutical properties and shows
hepatoprotective potential. However, the hepatoprotective mechanism of RA needs to be …

Resveratrol ameliorates carbon tetrachloride-induced acute liver injury in mice

G Fan, JJ Tang, M Bhadauria, SK Nirala, F Dai… - Environmental …, 2009 - Elsevier
Present investigation aimed to evaluate the hepatoprotective potential of resveratrol
(30mg/kg, po) in mice following two different routes (po and sc) of exposure to carbon …

[HTML][HTML] Naringin prevents carbon tetrachloride-induced acute liver injury in mice

D Dong, L Xu, L Yin, Y Qi, J Peng - Journal of Functional Foods, 2015 - Elsevier
The protective effects and mechanisms of action of naringin (Nar) against carbon
tetrachloride (CCl 4)-induced hepatic injury in mice were investigated. The results showed …

Rosmarinic acid attenuates hepatic ischemia and reperfusion injury in rats

LNZ Ramalho, ÂAC Pasta, VA Terra… - Food and chemical …, 2014 - Elsevier
Rosmarinic acid (RosmA) demonstrates antioxidant and anti-inflammatory properties. We
investigated the effect of RosmA on liver ischemia/reperfusion injury. Rats were submitted to …

Protective effect of carnosol on CCl4-induced acute liver damage in rats

JI Sotelo-Félix, D Martinez-Fong… - European Journal of …, 2002 - journals.lww.com
Background We recently reported that Rosmarinus officinalis (Lamiaceae) may alleviate CCl
4-induced acute hepatotoxicity in rats, possibly blocking the formation of free radicals …

Evaluation of the effectiveness of Rosmarinus officinalis (Lamiaceae) in the alleviation of carbon tetrachloride-induced acute hepatotoxicity in the rat

JI Sotelo-Félix, D Martinez-Fong, P Muriel… - Journal of …, 2002 - Elsevier
The effect of oral administration of Rosmarinus officinalis L.(Lamiaceae) on CCl4-induced
acute liver injury was investigated. Rats were daily treated with the plant extract at a dose of …

Hepatoprotective activity of raspberry ketone is mediated via inhibition of the NF-κB/TNF-α/caspase axis and mitochondrial apoptosis in chemically induced acute …

D Fouad, A Badr, HA Attia - Toxicology research, 2019 - academic.oup.com
Raspberry Ketone (RK) is a natural phenolic compound which is marketed nowadays as a
popular weight-reducing remedy, with reported antioxidant and anti-inflammatory activities …

Mulberry water extracts (MWEs) ameliorated carbon tetrachloride-induced liver damages in rat

LS Hsu, HH Ho, MC Lin, CC Chyau, JS Peng… - Food and chemical …, 2012 - Elsevier
Mulberry extracts are antidiabetic and antihyperlipidemic, as well as preventive of
cardiovascular disease. The current study investigates the protective mechanisms of …

S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice

J Xiao, EC Liong, MT Ling, YP Ching, ML Fung… - European journal of …, 2012 - Springer
Purpose To study the protective effects and underlying molecular mechanisms of SAMC on
carbon tetrachloride (CCl 4)-induced acute hepatotoxicity in the mouse model. Methods …