Long wavelength–emissive Ru (II) metallacycle–based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment
Y Xu, C Li, X Ma, W Tuo, L Tu, X Li… - Proceedings of the …, 2022 - National Acad Sciences
Ruthenium (Ru) complexes are developed as latent emissive photosensitizers for cancer
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …
Rationally designed Ru (ii)-metallacycle chemo-phototheranostic that emits beyond 1000 nm
C Li, Y Xu, L Tu, M Choi, Y Fan, X Chen, JL Sessler… - Chemical …, 2022 - pubs.rsc.org
Ruthenium complexes are emerging as potential complements to platinum drugs. They also
show promise as photo-diagnostic and therapeutic agents. However, most ruthenium …
show promise as photo-diagnostic and therapeutic agents. However, most ruthenium …
Construction of emissive ruthenium (II) metallacycle over 1000 nm wavelength for in vivo biomedical applications
Y Xu, C Li, S Lu, Z Wang, S Liu, X Yu, X Li… - Nature …, 2022 - nature.com
Although Ru (II)-based agents are expected to be promising candidates for substituting Pt-
drug, their in vivo biomedical applications are still limited by the short excitation/emission …
drug, their in vivo biomedical applications are still limited by the short excitation/emission …
NIR‐II Emissive Ru (II) Metallacycle Assisting Fluorescence Imaging and Cancer Therapy
Despite the success of emissive Ruthenium (Ru) agents in biomedicine, problems such as
the visible‐light excitation/emission and single chemo‐or phototherapy modality still hamper …
the visible‐light excitation/emission and single chemo‐or phototherapy modality still hamper …
Acceptor engineering of metallacycles with high phototoxicity indices for safe and effective photodynamic therapy
C Li, L Tu, J Yang, C Liu, Y Xu, J Li, W Tuo… - Chemical …, 2023 - pubs.rsc.org
Although metallacycle-based photosensitizers have attracted increasing attention in
biomedicine, their clinical application has been hindered by their inherent dark toxicity and …
biomedicine, their clinical application has been hindered by their inherent dark toxicity and …
Heterometallic Ru–Pt metallacycle for two-photon photodynamic therapy
As an effective and noninvasive treatment of various diseases, photodynamic therapy (PTD)
relies on the combination of light, a photosensitizer, and oxygen to generate cytotoxic …
relies on the combination of light, a photosensitizer, and oxygen to generate cytotoxic …
Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …
photochemical properties of transition metal complexes for diagnostic and therapeutic …
Design of a Metallacycle‐Based Supramolecular Photosensitizer for In Vivo Image‐Guided Photodynamic Inactivation of Bacteria
Y Xu, W Tuo, L Yang, Y Sun, C Li, X Chen… - Angewandte …, 2022 - Wiley Online Library
Bacterial infection is one of the greatest threats to public health. In vivo real‐time monitoring
and effective treatment of infected sites through non‐invasive techniques, remain a …
and effective treatment of infected sites through non‐invasive techniques, remain a …
Engineered metallacycle‐based supramolecular Photosensitizers for effective Photodynamic Therapy
Although metallacycle‐based supramolecular photosensitizers (PSs) have attracted
increasing attention in biomedicine, their clinical translation is still hindered by their inherent …
increasing attention in biomedicine, their clinical translation is still hindered by their inherent …
Ru(II) Dyads Derived from 2-(1-Pyrenyl)-1H-imidazo[4,5-f][1,10]phenanthroline: Versatile Photosensitizers for Photodynamic Applications
M Stephenson, C Reichardt, M Pinto… - The Journal of …, 2014 - ACS Publications
Combining the best attributes of organic photosensitizers with those of coordination
complexes is an elegant way to achieve prolonged excited state lifetimes in Ru (II) dyads …
complexes is an elegant way to achieve prolonged excited state lifetimes in Ru (II) dyads …