Overview: Cancer remains a significant global health challenge, accounting for one in eight
deaths worldwide. Chemotherapy, the primary cancer treatment, is often limited by drug …

Introduction; Cancer is recognized as a one of the major health hazards worldwide and also
accounts for one in eight deaths globally. Chemotherapy, which is considered a principal …

Background: This study aimed to develop a novel drug formulation using
polybutylcyanoacrylate (PBCA) nanoparticles to deliver cisplatin, a commonly used …

Breast cancer is the most common cancer and the second cause of cancer‐related death in
women worldwide. Chemotherapy of disease is impeded by subsequent relapse and …

The hyaluronic acid (HA) coated poly (butyl cyanoacrylate)(PBCA) nanoparticles were
synthesized through radical polymerization of butyl cyanoarylate (BCA) initiated by cerium …

Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

Prolonged use of anticancer drug like Paclitaxel increases the level of transcription factor
nuclear factor kappa B (NFƘB) which increases drug resistance in cancer cells. Multi-drug …

This study aims to improve the cytotoxicity and potency of cisplatin-loaded
polybutylcyanoacrylate (PBCA) nanoparticles (NPs) for the treatment of lung cancer through …

In recent decades, many novel methods by using nanoparticles (NPs) have been
investigated for diagnosis, drug delivery and treatment of cancer. Accordingly, the potential …

The aim of the present study is the preparation and physicochemical characterization of
chlorambucil-loaded poly (butylcyanoacrylate) nanoparticles. Chlorambucil is a lipophilic …