Melanin protects Cryptococcus neoformans from spaceflight effects

RJB Cordero, Q Dragotakes, PJ Friello… - Environmental …, 2022 - Wiley Online Library
As human activity in space continues to increase, understanding how biological assets
respond to spaceflight conditions is becoming more important. Spaceflight conditions …

[引用][C] Melanin for space travel radioprotection

RJB Cordero - Environmental Microbiology, 2017 - Wiley Online Library
For those aiming for deep space travel, ionizing radiation is an important problem (Durante
and Cucinotta, 2011). As one travels beyond Earth's protective gas atmosphere and …

Transcriptomic analysis reveals the relationship of melanization to growth and resistance to gamma radiation in Cryptococcus neoformans

Z Schultzhaus, A Chen, S Kim, I Shuryak… - Environmental …, 2019 - Wiley Online Library
The pathogenic fungus Cryptococcus neoformans produces melanin within its cell wall for
infection and resistance against external stresses such as exposure to UV, temperature …

Melanin is effective in protecting fast and slow growing fungi from various types of ionizing radiation

C Pacelli, RA Bryan, S Onofri… - Environmental …, 2017 - Wiley Online Library
Melanin is a ubiquitous pigment with unique physicochemical properties. The resistance of
melanized fungi to cosmic and terrestrial ionizing radiation suggests that melanin also plays …

Melanization affects susceptibility of Cryptococcus neoformans to heat and cold

ÁL Rosas, A Casadevall - FEMS microbiology letters, 1997 - academic.oup.com
Cryptococcus neoformans can synthesize melanin from a variety of substrates, including L-
dopa (l-3, 4-dihydroxyphenylalanine). Growth in minimal medium with L-dopa resulted in …

Melanization decreases the susceptibility of Cryptococcus neoformans to enzymatic degradation

ÁL Rosas, A Casadevall - Mycopathologia, 2001 - Springer
Cryptococcus neoformans is a free-living fungus that is primarily found in soils contaminated
with avian excreta. Recent studies have shown that C. neoformans can synthesize melanins …

Protection of Melanized Cryptococcus neoformans from Lethal Dose Gamma Irradiation Involves Changes in Melanin's Chemical Structure and Paramagnetism

A Khajo, RA Bryan, M Friedman, RM Burger… - PLoS …, 2011 - journals.plos.org
Certain fungi thrive in highly radioactive environments including the defunct Chernobyl
nuclear reactor. Cryptococcus neoformans (C. neoformans), which uses L-3, 4 …

Induction by Klebsiella aerogenes of a Melanin-Like Pigment in Cryptococcus neoformans

S Frases, S Chaskes, E Dadachova… - Applied and …, 2006 - Am Soc Microbiol
While studying the interaction of Cryptococcus neoformans with Dictyostelium discoideum,
we noticed that yeast colonies in agar with a feeder lawn of Klebsiella aerogenes were …

Kombucha multimicrobial community under simulated spaceflight and martian conditions

O Podolich, I Zaets, O Kukharenko, I Orlovska… - Astrobiology, 2017 - liebertpub.com
Kombucha microbial community (KMC) produces a cellulose-based biopolymer of industrial
importance and a probiotic beverage. KMC-derived cellulose-based pellicle film is known as …

MARSBOx: fungal and bacterial endurance from a balloon-flown analog mission in the stratosphere

M Cortesão, K Siems, S Koch… - Frontiers in …, 2021 - frontiersin.org
Whether terrestrial life can withstand the martian environment is of paramount interest for
planetary protection measures and space exploration. To understand microbial survival …