[HTML][HTML] Host-parasite interactions during Plasmodium infection: Implications for immunotherapies

P Chandley, R Ranjan, S Kumar, S Rohatgi - Frontiers in Immunology, 2023 - frontiersin.org
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Immune evasion by malaria parasites: a challenge for vaccine development

S Casares, TL Richie - Current opinion in immunology, 2009 - Elsevier
Malaria is a deadly infectious disease that affects one to two billion people and kills up to
one million children yearly. Despite decades of intensive research, we are still lacking an …

Harnessing immune responses against Plasmodium for rational vaccine design

B Douradinha, DL Doolan - Trends in parasitology, 2011 - cell.com
In recent years, groundbreaking advances have been made in understanding the biology of
and immune mechanisms against the Plasmodium spp. parasite, the causative agent of …

[HTML][HTML] Host–parasite interactions in human malaria: clinical implications of basic research

P Acharya, M Garg, P Kumar, A Munjal… - Frontiers in …, 2017 - frontiersin.org
The malaria parasite, Plasmodium, is one of the oldest parasites documented to infect
humans and has proven particularly hard to eradicate. One of the major hurdles in designing …

Expanding the antimalarial toolkit: Targeting host–parasite interactions

J Langhorne, PE Duffy - Journal of Experimental Medicine, 2016 - rupress.org
Recent successes in malaria control are threatened by drug-resistant Plasmodium parasites
and insecticide-resistant Anopheles mosquitoes, and first generation vaccines offer only …

Immune responses in malaria

CA Long, F Zavala - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
Evidence accumulated through the years clearly indicates that antiparasite immune
responses can efficiently control malaria parasite infection at all development stages, and …

A bite to fight: front-line innate immune defenses against malaria parasites

S Tannous, E Ghanem - Pathogens and global health, 2018 - Taylor & Francis
Malaria infection caused by Plasmodium parasites remains a major health burden
worldwide especially in the tropics and subtropics. Plasmodium exhibits a complex life cycle …

[HTML][HTML] Immune escape strategies of malaria parasites

PS Gomes, J Bhardwaj, J Rivera-Correa… - Frontiers in …, 2016 - frontiersin.org
Malaria is one of the most life-threatening infectious diseases worldwide. Immunity to
malaria is slow and short-lived despite the repeated parasite exposure in endemic areas …

Host immune evasion strategies of malaria blood stage parasite

XY Yam, PR Preiser - Molecular BioSystems, 2017 - pubs.rsc.org
Host immune evasion is a key strategy for the continual survival of many microbial
pathogens including Apicomplexan protozoan: Plasmodium spp., the causative agent of …

[HTML][HTML] The case for exploiting cross-species epitopes in malaria vaccine design

CJ Mitran, SK Yanow - Frontiers in Immunology, 2020 - frontiersin.org
The infection dynamics between different species of Plasmodium that infect the same human
host can both suppress and exacerbate disease. This could arise from inter-parasite …