Fertilization failure refers to the failure in the pronucleus formation, evaluating 16-18 h post
in vitro fertilization or intracytoplasmic sperm injection. It can be caused by sperm, oocytes …

Fertilization failure during assisted reproductive technologies (ART) is often unpredictable,
as this failure is encountered only after in vitro fertilization (IVF) and intracytoplasmic sperm …

BACKGROUND The complexity of fertilization failure during assisted reproductive
technologies (ART) is often under-appreciated, as this failure can occur at any number of …

BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Fertilization failures diminish the number of zygotes available for fertility treatment. When
considering the potential etiologies of fertilization failures, oocyte determinants merit careful …

BACKGROUND Infertility affects between 10 and 16% of couples worldwide. Twenty to 30%
of cases of infertility are due to a male factor, 20–35% to a female factor, and 25–40% are …

Subfertility, defined as the inability to conceive within 1 year of unprotected intercourse,
affects 10–15% of couples. In up to 55% of couples, the male partner is diagnosed with …

BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

BACKGROUND Total fertilization failure (TFF) is the failure of all metaphase II oocytes to
fertilize in ART cycles. The phenomenon represents a known cause of infertility, affecting 1 …

Purpose. The purpose of this review is to summarize science-based new treatments for
human reproductive failure and future developments. Results. First will be discussed …