Recently we proposed that the antineoplastic properties observed in vivo for alkyl-
lysophospholipid and alkylphosphocholine analogues are a direct consequence of the …

The alkyllysophospholipid (ALP) analogues Mitelfosine and Edelfosine are anticancer drugs
whose mode of action is still the subject of debate. It is agreed that the primary interaction of …

When interacting with phospholipid in an aqueous environment, amphotericin B forms
unusual structures of markedly reduced toxicity (Janoff et al.(1988) Proc. Natl. Acad. Sci …

We propose classifying surfactants with respect to their effect on membrane order, which is
derived from the time-resolved fluorescence anisotropy of DPH. This may help in …

The elastic properties of membrane bilayers are key parameters that control its deformation
and can be affected by pharmacological agents. Our previous atomic force microscopy …

Surface-active amphiphiles find applications in a wide range of areas of industry such as
agrochemicals, personal care, and pharmaceuticals. In many of these applications …

The hydrophobic surfactant proteins, SP-B and SP-C, greatly accelerate the adsorption of
the surfactant lipids to an air/water interface. Previous studies of factors that affect curvature …

Triton X-100 (T) in its monomeric form has been found to induce the leakage of 5 (6)-
carboxyfluorescein (CF) from tightly packed gel-phase vesicles derived from l, 2-dipalmitoyl …

Cationic amino acid-based surfactants are known to interact with the lipid bilayer of
microorganism resulting in cell death through a disruption of the membrane topology. To …

Purpose. To gain some mechanistic understanding of surfactant-inducedmembrane
permeabilization and identify a surfactant physicalproperty that can be used as a predictor …