Biological systems perceive and respond to mechanical forces, generating mechanical cues
to regulate life processes. Analyzing biomechanical forces has profound significance for …

At the nanoscale, pushing, pulling, and shearing forces drive biochemical processes in
development and remodeling as well as in wound healing and disease progression …

Cellular processes and functions can be regulated by mechanical forces. Nanodevices that
can measure and manipulate these forces are critical tools in chemical and cellular biology …

DNA is both a fundamental building block of life and a fascinating natural polymer. The
advent of single-molecule manipulation tools made it possible to exert controlled force on …

Single-molecule force measurement techniques provide unique opportunities to investigate
simple molecular interactions and complicated force-induced cell responses. This has …

Cells constantly experience mechanical forces during growth and development. Increasing
evidence suggests that mechanical forces can regulate cellular processes such as …

Single molecule force spectroscopy is a powerful approach to probe the structure,
conformational changes, and kinetic properties of biological and synthetic macromolecules …

The mechanical properties of DNA have enabled it to be a structural and sensory element in
many nanotechnology applications. While specific base-pairing interactions and secondary …

Structural DNA nanotechnology is a rapidly emerging field that has demonstrated great
potential for applications such as single molecule sensing, drug delivery, and templating …

Cells use protein-based mechanosensors to measure the physical properties of their
surroundings. Synthetic tension sensors made of proteins, DNA, and other molecular …