[HTML][HTML] The roles of miRNA in glioblastoma tumor cell communication: diplomatic and aggressive negotiations
A Buruiană, ȘI Florian, AI Florian, TL Timiș… - International journal of …, 2020 - mdpi.com
Glioblastoma (GBM) consists of a heterogeneous collection of competing cellular clones
which communicate with each other and with the tumor microenvironment (TME) …
which communicate with each other and with the tumor microenvironment (TME) …
MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma
Malignant brain tumors, including glioblastoma (GBM), are among the most lethal human
cancers, due to their tremendous invasive capacity and limited therapeutic options. Despite …
cancers, due to their tremendous invasive capacity and limited therapeutic options. Despite …
MiR-124 inhibits STAT3 signaling to enhance T cell–mediated immune clearance of glioma
Abstract miRNAs (miR) have been shown to modulate critical gene transcripts involved in
tumorigenesis, but their role in tumor-mediated immunosuppression is largely unknown. On …
tumorigenesis, but their role in tumor-mediated immunosuppression is largely unknown. On …
[HTML][HTML] Gap junctions modulate glioma invasion by direct transfer of microRNA
X Hong, WC Sin, AL Harris, CC Naus - Oncotarget, 2015 - ncbi.nlm.nih.gov
The invasiveness of high-grade glioma is the primary reason for poor survival following
treatment. Interaction between glioma cells and surrounding astrocytes are crucial to …
treatment. Interaction between glioma cells and surrounding astrocytes are crucial to …
miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …
Targeted delivery of miRNA based therapeuticals in the clinical management of Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most aggressive (WHO grade IV) form of diffuse
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …
miR-145 inhibits migration and invasion of glioma stem cells by targeting ABCG2
L Shi, Z Wang, G Sun, Y Wan, J Guo, X Fu - Neuromolecular medicine, 2014 - Springer
Despite advances in clinical therapies and technologies, the prognosis for patients with
malignant glioma is poor. Our previous research demonstrated that glioma stem cells …
malignant glioma is poor. Our previous research demonstrated that glioma stem cells …
[HTML][HTML] miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2
JC Loftus, JTD Ross, KM Paquette, VM Paulino… - PloS one, 2012 - journals.plos.org
Background Glioblastoma (GB) is the most common and lethal type of primary brain tumor.
Clinical outcome remains poor and is essentially palliative due to the highly invasive nature …
Clinical outcome remains poor and is essentially palliative due to the highly invasive nature …
miRNA-182 and the regulation of the glioblastoma phenotype-toward miRNA-based precision therapeutics
FM Kouri, C Ritner, AH Stegh - Cell cycle, 2015 - Taylor & Francis
Glioblastoma (GBM) is an incurable cancer, with survival rates of just 14-16 months after
diagnosis. Functional genomics have identified numerous genetic events involved in GBM …
diagnosis. Functional genomics have identified numerous genetic events involved in GBM …
[HTML][HTML] Role of microRNAs in glioblastoma
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …