Wolbachia as translational science: controlling mosquito-borne pathogens

EP Caragata, HLC Dutra, PHF Sucupira… - Trends in …, 2021 - cell.com
In this review we examine how exploiting the Wolbachia–mosquito relationship has become
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …

Exploiting intimate relationships: controlling mosquito-transmitted disease with Wolbachia

EP Caragata, HLC Dutra, LA Moreira - Trends in parasitology, 2016 - cell.com
Mosquito-transmitted diseases impose a growing burden on human health, and current
control strategies have proven insufficient to stem the tide. The bacterium Wolbachia is a …

Wolbachia pipientis: an expanding bag of tricks to explore for disease control

PE Cook, EA McGraw - Trends in parasitology, 2010 - cell.com
Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread
among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of …

Wolbachia Biocontrol Strategies for Arboviral Diseases and the Potential Influence of Resident Wolbachia Strains in Mosquitoes

CL Jeffries, T Walker - Current Tropical Medicine Reports, 2016 - Springer
Arboviruses transmitted by mosquitoes are a major cause of human disease worldwide. The
absence of vaccines and effective vector control strategies has resulted in the need for novel …

Wolbachia: can we save lives with a great pandemic?

D LePage, SR Bordenstein - Trends in parasitology, 2013 - cell.com
Wolbachia pipientis is the most common bacterial infection in the animal world and wields a
vast influence on invertebrate reproduction, sex determination, speciation, and behavior …

The Impact of Wolbachia on Virus Infection in Mosquitoes

KN Johnson - Viruses, 2015 - mdpi.com
Mosquito-borne viruses such as dengue, West Nile and chikungunya viruses cause
significant morbidity and mortality in human populations. Since current methods are not …

Wolbachia-Conferred Antiviral Protection Is Determined by Developmental Temperature

E Chrostek, N Martins, MS Marialva, L Teixeira - MBio, 2021 - Am Soc Microbiol
Wolbachia is a maternally transmitted bacterium that is widespread in arthropods and filarial
nematodes and confers strong antiviral protection in Drosophila melanogaster and other …

Conflict in the Intracellular Lives of Endosymbionts and Viruses: A Mechanistic Look at Wolbachia-Mediated Pathogen-blocking

ARI Lindsey, T Bhattacharya, ILG Newton, RW Hardy - Viruses, 2018 - mdpi.com
At the forefront of vector control efforts are strategies that leverage host-microbe associations
to reduce vectorial capacity. The most promising of these efforts employs Wolbachia, a …

Antiviral protection and the importance of Wolbachia density and tissue tropism in Drosophila simulans

SE Osborne, I Iturbe-Ormaetxe… - Applied and …, 2012 - Am Soc Microbiol
Wolbachia, a maternally transmitted endosymbiont of insects, is increasingly being seen as
an effective biological control agent that can interfere with transmission of pathogens …

Evolutionary Ecology of Wolbachia Releases for Disease Control

PA Ross, M Turelli, AA Hoffmann - Annual review of genetics, 2019 - annualreviews.org
Wolbachia is an endosymbiotic Alphaproteobacteria that can suppress insect-borne
diseases through decreasing host virus transmission (population replacement) or through …