Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma

C Duggan, L Onstad, S Hardikar, PL Blount… - Clinical …, 2013 - Elsevier
Background & Aims Individuals with Barrett's esophagus (BE) have an increased risk of
developing esophageal adenocarcinoma (EA). Obesity contributes to the development of BE …

Serum leptin and adiponectin levels and risk of Barrett's esophagus and intestinal metaplasia of the gastroesophageal junction

OM Thompson, SAA Beresford, EA Kirk, MP Bronner… - …, 2010 - Wiley Online Library
Persons diagnosed with Barrett's esophagus (BE) are at increased risk of developing
esophageal adenocarcinoma (EA). Obesity is a major risk factor for both BE and EA. The …

Central adiposity and risk of Barrett's esophagus

ZR Edelstein, DC Farrow, MP Bronner, SN Rosen… - Gastroenterology, 2007 - Elsevier
Background & Aims: Aside from chronic reflux, the etiology of Barrett's esophagus (BE)
remains largely unknown. This case-control study investigated body mass index (BMI) …

Leptin and the risk of Barrett's oesophagus

BJ Kendall, GA Macdonald, NK Hayward, JB Prins… - Gut, 2008 - gut.bmj.com
Background: Obesity is associated with increased risks of Barrett's oesophagus and
oesophageal adenocarcinoma. Alterations in serum leptin and adiponectin, obesity-related …

Association of serum levels of adipokines and insulin with risk of Barrett's esophagus: a systematic review and meta-analysis

AK Chandar, S Devanna, C Lu, S Singh, K Greer… - Clinical …, 2015 - Elsevier
Background & Aims Metabolically active visceral fat may be associated with esophageal
inflammation, metaplasia, and neoplasia. We performed a meta-analysis to evaluate the …

A systematic review and meta-analysis of the riskof increasing adiposity on Barrett's esophagus

MB Cook, DC Greenwood, LJ Hardie… - Official journal of the …, 2008 - journals.lww.com
OBJECTIVES Esophageal adenocarcinoma and its precursor lesion, Barrett's esophagus,
are increasing in incidence in western populations. Gastroesophageal reflux disease …

Obesity and risk of esophageal adenocarcinoma and Barrett's esophagus: a Mendelian randomization study

AP Thrift, NJ Shaheen, MD Gammon… - Journal of the …, 2014 - academic.oup.com
Background Data from observational studies suggest that body mass index (BMI) is causally
related to esophageal adenocarcinoma (EAC) and its precursor, Barrett's esophagus (BE) …

Abdominal obesity and the risk of Barrett's esophagus

HB El-Serag, P Kvapil, J Hacken-Bitar… - Official journal of the …, 2005 - journals.lww.com
BACKGROUND The association between overweight/obesity and the risk of Barrett's
esophagus (BE) is unclear. Further, the association between body fat distribution and the …

Role of obesity in the pathogenesis and progression of Barrett's esophagus

AK Chandar, PG Iyer - Gastroenterology Clinics, 2015 - gastro.theclinics.com
An exponential increase in the prevalence of obesity has been observed in the United
States in recent decades, 1 paralleled by a comparable increase in the incidence of …

A prospective cohort study on overweight, smoking, alcohol consumption, and risk of Barrett's esophagus

J Steevens, LJ Schouten, ALC Driessen… - … Biomarkers & Prevention, 2011 - AACR
Background: Barrett's esophagus (BE) is a precursor lesion of esophageal adenocarcinoma.
Besides gastroesophageal reflux, possible risk factors for BE include overweight, cigarette …