Precision medicine refers to the choosing of targeted therapies based on genetic data. Due
to the increasing availability of data from large-scale tumor genome sequencing projects …

Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …

The inherent molecular heterogeneity of metastatic tumors and the ability of cancer
genomes to dynamically evolve are not properly captured by tissue specimens. Analysis of …

Liquid biopsy is based on minimally invasive blood tests and has a high potential to
significantly change the therapeutic strategy in cancer patients, providing an extremely …

Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

Predictive biomarkers aid selection of personalized therapy targeted to molecular alterations
within an individual's tumor. Patients' responses to targeted therapies are commonly …

During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …

Editorial summary Progress in sensitive analytical approaches has opened new avenues for
the detection of cells or products such as circulating cell-free DNA released by tumors …

In the era of personalized medicine detection of the molecular drivers of tumors and of
specific DNA mutations predicting response or resistance to targeted agents has become …

Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …