Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …

G-quadruplexes (G4s) are noncanonical nucleic acid structures involved in the regulation of
key cellular processes, such as transcription and replication. Since their discovery, G4s have …

Viruses are the most abundant organisms on our planet, affecting all living beings: some of
them are responsible for massive epidemics that concern health, national economies and …

With the emergence of new viruses in the human population and the fast mutation rates of
existing viruses, new antiviral targets and compounds are needed. Most existing antiviral …

Guanine-rich DNA and RNA sequences can fold into noncanonical nucleic acid structures
called G-quadruplexes (G4s). Since the discovery that these structures may act as scaffolds …

G-rich nucleic acids can form non-canonical G-quadruplex structures (G4s) in which four
guanines fold in a planar arrangement through Hoogsteen hydrogen bonds. Although many …

A G-quadruplex (G4) is a four-stranded nucleic acid secondary structure maintained by
Hoogsteen hydrogen bonds established between four guanines. Experimental studies and …

DNA can form several secondary structures besides the classic double helix: one that has
received much attention in recent years is the G-quadruplex (G4). This is a stable four …

Guanine-rich nucleic acids can fold into G-quadruplexes, secondary structures implicated in
important regulatory functions at the genomic level in humans, prokaryotes and viruses. The …

G‐quadruplexes (G4) are four‐stranded structures formed from guanine‐rich
oligonucleotides. Their defined 3D structures and polymorphic nature set them apart from …