[PDF][PDF] Glycaemic Control in Diabetes

D Müller-Wieland, J Brandts, M Verket… - … and Treatment of …, 2021 - library.oapen.org
Reduction of glucose is the hallmark of diabetes therapy proven to reduce microand macro-
vascular risk in patients with type 1 diabetes. However glucoselowering efficacy trials in type …

GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes

N Marx, M Husain, M Lehrke, S Verma, N Sattar - Circulation, 2022 - Am Heart Assoc
Patients with type 2 diabetes are at high risk for development of cardiovascular disease,
including myocardial infarction, stroke, heart failure, and cardiovascular death. Multiple large …

[HTML][HTML] Cardiovascular benefits of GLP-1 receptor agonism: is inflammation a key?

N Marx, P Libby - JACC: Basic to Translational Science, 2018 - jacc.org
We stand on the threshold of an exciting area when at long last we have novel antidiabetic
therapies proven to reduce cardiovascular events. Recent large-scale trials have finally …

Treatment of diabetes mellitus has borne much fruit in the prevention of cardiovascular disease

H Yagyu, H Shimano - Journal of Diabetes Investigation, 2022 - Wiley Online Library
Cardiovascular (CV) disease is the most alarming complication of diabetes mellitus (DM),
and a strategy aiming at cardiovascular event prevention in diabetes mellitus has long been …

The intersection of diabetes and cardiovascular disease—a focus on new therapies

DS Dhindsa, PB Sandesara… - Frontiers in Cardiovascular …, 2018 - frontiersin.org
Diabetes is a leading cause of cardiovascular disease and its associated morbidity. While
the medical community has had access to numerous glucose lowering therapies over the …

SGLT-2 inhibitors and GLP-1 agonists: first-line therapy for diabetes with established cardiovascular disease

AP Sajja, AK Dey, A Guha, Y Elnabawi… - Journal of …, 2019 - journals.sagepub.com
There is a growing body of evidence that diabetes represents a significant and largely
modifiable risk factor for cardiovascular disease (CVD). It is known to markedly increase the …

Clinical implications of cardiovascular outcome trials in type 2 diabetes

LG Mellbin, A Wang, L Rydén - Herz, 2019 - Springer
Cardiovascular disease (CVD) is the main reason for premature death in patients with type 2
diabetes. Hyperglycemia, the hallmark of diabetes, has long been considered the link …

The current landscape for diabetes treatment: Preventing diabetes-associated CV risk

A Dardano, C Bianchi, M Garofolo, S Del Prato - Atherosclerosis, 2024 - Elsevier
Despite the risk of atherosclerosis has progressively declined over the past few decades,
subjects with type 2 diabetes mellitus (T2DM) continue to experience substantial excess of …

[HTML][HTML] SGLT-2 inhibitors and cardiovascular protection: lessons and gaps in understanding the current outcome trials and possible benefits of combining SGLT-2 …

E Abdelgadir, F Rashid, A Bashier… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Landmark trials on diabetes control have shown variable results in terms of cardiovascular
benefits, with the majority showing a favorable effect of glycemic control on microvascular …

Diabetes mellitus and cardiovascular disease: Emerging therapeutic approaches

AM Schmidt - Arteriosclerosis, thrombosis, and vascular biology, 2019 - Am Heart Assoc
Cardiovascular disease remains a leading cause of morbidity and mortality in people with
types 1 or 2 diabetes mellitus. Although beneficial roles for strict control of hyperglycemia …