Improving cancer immunotherapy through nanotechnology

MS Goldberg - Nature Reviews Cancer, 2019 - nature.com
Abstract The 2018 Nobel Prize in Physiology or Medicine was awarded to pioneers in the
field of cancer immunotherapy, as the utility of leveraging a patient's coordinated and …

Immunoengineering: how nanotechnology can enhance cancer immunotherapy

MS Goldberg - Cell, 2015 - cell.com
Although cancer immunotherapy can lead to durable outcomes, the percentage of patients
who respond to this disruptive approach remains modest to date. Encouragingly …

Nano-enhanced cancer immunotherapy: immunology encounters nanotechnology

E Bockamp, S Rosigkeit, D Siegl, D Schuppan - Cells, 2020 - mdpi.com
Cancer immunotherapy utilizes the immune system to fight cancer and has already moved
from the laboratory to clinical application. However, and despite excellent therapeutic …

Molecular and nanoengineering approaches towards activatable cancer immunotherapy

C Zhang, K Pu - Chemical Society Reviews, 2020 - pubs.rsc.org
Cancer immunotherapy is an emerging treatment strategy that modulates the immune
system to fight against cancer. Although several immunotherapeutic agents have been …

Nano-immunotherapy: Overcoming tumour immune evasion

ML Guevara, F Persano, S Persano - Seminars in Cancer Biology, 2021 - Elsevier
Immunotherapy is emerging as a groundbreaking cancer treatment, offering the
unprecedented opportunity to effectively treat and in several cases, even cure previously …

Designing nanomedicine for immuno-oncology

W Jiang, CA Von Roemeling, Y Chen, Y Qie… - Nature Biomedical …, 2017 - nature.com
Two major obstacles facing cancer nanomedicine are the tendency of nanoparticles to be
taken up by normal tissues and organs and the nanoparticles' inability to efficiently penetrate …

Considerations for designing preclinical cancer immune nanomedicine studies

W Jiang, Y Wang, JA Wargo, FF Lang… - Nature nanotechnology, 2021 - nature.com
Immunotherapy is known to be clinically beneficial for cancer patients and in many cases
represents the new standard of care. Because of this success, the interest in integrating …

Delivery technologies for cancer immunotherapy

RS Riley, CH June, R Langer, MJ Mitchell - Nature reviews Drug …, 2019 - nature.com
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Enhancing cancer immunotherapy with nanomedicine

DJ Irvine, EL Dane - Nature Reviews Immunology, 2020 - nature.com
Therapeutic targeting of the immune system in cancer is now a clinical reality and marked
successes have been achieved, most notably through the use of checkpoint blockade …

[HTML][HTML] Delivering safer immunotherapies for cancer

L Milling, Y Zhang, DJ Irvine - Advanced drug delivery reviews, 2017 - Elsevier
Cancer immunotherapy is now a powerful clinical reality, with a steady progression of new
drug approvals and a massive pipeline of additional treatments in clinical and preclinical …