Background This study evaluated the risk of long-term analgesic use after low-risk surgery in
older adults not previously prescribed analgesics. Methods We conducted a retrospective …

Methods| We conducted a retrospective cohort study that was approved by the research
ethics board at Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. The …

Importance Chronic opioid use imposes a substantial burden in terms of morbidity and
economic costs. Whether opioid-naive patients undergoing surgery are at increased risk for …

Objective: Evaluate the association between postoperative opioid prescribing and new
persistent opioid use. Summary Background Data: Opioid-nave patients who develop new …

Importance Despite increased focus on reducing opioid prescribing for long-term pain, little
is known regarding the incidence and risk factors for persistent opioid use after surgery …

Objective. This study aims to determine 1) the epidemiology of perioperative opioid use; and
2) the association between patterns of preoperative opioid use and time-to-cessation of …

Post-surgical opioid prescribing intended for the short-term management of acute pain may
lead to long-term opioid use. This study was undertaken to determine the prevalence of …

Objective: To examine the extent to which preoperative opioid use is correlated with
healthcare utilization and costs following elective surgical procedures. Summary …

Background Although new persistent opioid use and high-risk prescribing have been
recognized as important postoperative complications among younger patients (18–64 years …

Objective: The aim of this study was to determine preoperative patient characteristics
associated with postoperative outpatient opioid use and assess the frequency of …