[PDF][PDF] Polyunsaturated fatty acids augment tumoricidal action of 5-fluorouracil on gastric cancer cells by their action on vascular endothelial growth factor, tumor …

H Yu, Y Liu, W Pan, S Shen, UN Das - Archives of Medical Science, 2015 - termedia.pl
Results: It was noted that combined treatment of 5-FU+ PUFAs on gastric carcinoma (MGC
and SGC) cells produced a significant growth inhibitory action compared with either agent …

Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro

J Dai, J Shen, W Pan, S Shen, UN Das - Lipids in health and disease, 2013 - Springer
Polyunsaturated fatty acids (PUFAs) have tumoricidal action, though the exact mechanism of
their action is not clear. The results of the present study showed that of all the fatty acids …

Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes

C Zhang, H Yu, X Ni, S Shen, UN Das - PloS one, 2015 - journals.plos.org
Background Colorectal cancer is common. Polyunsaturated fatty acids (PUFAs) exert growth-
inhibitory and pro-apoptotic effects on colon cancer cells. Metabolites of PUFAs such as …

n‐3 Polyunsaturated fatty acids enhance the antitumor effect of 5‐fluorouracil by inhibiting bcl‐2 and mutant‐p53

YZ Tan, WG Huang, FY Chen, J Li… - European Journal of …, 2013 - Wiley Online Library
The study determined whether n‐3 polyunsaturated fatty acids (n‐3 PUFAs) enhance the
chemotherapeutic ability of 5‐fluorouracil (5‐FU) to affect bcl‐2 and mutant‐p53 (mt‐p53) …

[PDF][PDF] Differential action of polyunsaturated fatty acids and eicosanoids on bleomycin-induced cytotoxicity to neuroblastoma cells and lymphocytes

S Polavarapu, BS Dwarakanath, UN Das - Archives of Medical Science, 2018 - termedia.pl
Results: PUFAs inhibited the growth of IMR-32 cells (EPA> DHA= AA> GLA= ALA> DGLA=
LA) significantly (p< 0.001) while prostaglandins were found to be not effective. Bleomycin …

Comparison of the inhibitory effect of polyunsaturated fatty acids on prostaglandin synthesis I oral squamous carcinoma cells

TMA Elattar, HS Lin - Prostaglandins, leukotrienes and essential fatty acids, 1989 - Elsevier
Polyunsaturated fatty acids (PUFAs) have been shown to suppress the growth rate of human
osteogenic sarcoma cells and to have selective cytotoxic acitivity against human cancer …

n‐6 and n‐3 Fatty acids and their metabolites augment inhibitory action of doxorubicin on the proliferation of human neuroblastoma (IMR‐32) cells by enhancing lipid …

AD Hari, VGM Naidu, UN Das - BioFactors, 2018 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) have growth inhibitory action on tumor cells possibly, by
augmenting free‐radical generation and accumulation of lipid peroxides. This study focused …

n-3 polyunsaturated fatty acids as signal transduction modulators and therapeutical agents in cancer

G Calviello, S Serini, P Palozza - Current Signal Transduction …, 2006 - ingentaconnect.com
Epidemiological and experimental studies have established the beneficial effects of n-3
polyunsaturated fatty acids (PUFAs) on cancer. In particular, wide information is available …

The effect of oral administration of PUFAs on the matrix metalloproteinase expression in gastric adenocarcinoma patients undergoing chemotherapy

M Khojastehfard, H Dolatkhah, MH Somi… - Nutrition and …, 2019 - Taylor & Francis
Objective: Gastric cancer is the third-leading cause of cancer-related mortality and the fifth
most common cancer globally. Polyunsaturated fatty acids (PUFAs) are considered as …

Antineoplastic effects of n-3 polyunsaturated fatty acids in combination with drugs and radiotherapy: preventive and therapeutic strategies

G Calviello, S Serini, E Piccioni, G Pessina - Nutrition and cancer, 2009 - Taylor & Francis
Many data support the beneficial effect of n-3 polyunsaturated fatty acids (PUFAs) as
chemopreventive and chemotherapeutic agents in the treatment of several chronic …